SMPD1 抗体 (AA 204-558)
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北京 101111
Quick Overview for SMPD1 抗体 (AA 204-558) (ABIN7600575)
抗原
See all SMPD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 204-558
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原理
- Anti-Smpd1 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Smpd1 Antibody (ABIN7600575). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse Smpd1 recombinant protein (Position: D204-M558).
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亚型
- IgG
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anti-Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1) (AA 391-419), (C-Term) antibody
SMPD1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB31029 unconjugated
anti-Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1) (AA 319-579) antibodySMPD1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1) (AA 70-340) antibodySMPD1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1) (AA 1-364) antibodySMPD1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H2 unconjugated
anti-Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1) (AA 391-419), (C-Term) antibodySMPD1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1) (AA 201-300) antibodySMPD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1) (AA 396-445) antibodySMPD1 适用: 人, 小鼠, 大鼠, Cow, 绵羊, 犬, 马, 兔, Pig, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1) (AA 391-419) antibodySMPD1 适用: 人 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SMPD1 (Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))
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别名
- Smpd1
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背景
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Synonyms: ATP-dependent RNA helicase DDX3X,3.6.4.13,DEAD box protein 3, X-chromosomal,DEAD box, X isoform,Helicase-like protein 2,HLP2,DDX3X,DBX, DDX3,
Tissue Specificity: Thymic medulla (at protein level). Prominently expressed in the small intestine, colon and appendix. Also found in thymus, spleen, lymph node and lung. The long form might be dominant in intestinal, and the short form in lymphoid tissues. Expressed by IL17 producing helper T-cells (Th17).
Background: Sphingomyelin phosphodiesterase 1 (SMPD1), also known as acid sphingomyelinase (ASM), is an enzyme that in humans is encoded by the SMPD1 gene. Enables acid sphingomyelin phosphodiesterase activity and zinc ion binding activity. Involved in ceramide biosynthetic process, positive regulation of apoptotic process, and response to ionizing radiation. Acts upstream of or within ceramide metabolic process, cholesterol metabolic process, and sphingomyelin catabolic process. Located in extracellular space. Is expressed in several structures, including alimentary system, integumental system, nervous system, sensory organ, and skeleton. Used to study Niemann-Pick disease. Human ortholog(s) of this gene implicated in Niemann-Pick disease, Niemann-Pick disease type A, and Niemann-Pick disease type B. Orthologous to human SMPD1 (sphingomyelin phosphodiesterase 1).
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分子量
- 70 kDa
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基因ID
- 20597
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UniProt
- Q04519
抗原
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