ACSS2 抗体 (AA 201-651)
Quick Overview for ACSS2 抗体 (AA 201-651) (ABIN7600569)
抗原
See all ACSS2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 201-651
-
原理
- Anti-ACSS2 Antibody Picoband®
-
交叉反应 (详细)
- No cross-reactivity with other proteins.
-
产品特性
- Anti-ACSS2 Antibody Picoband® (ABIN7600569). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human ACSS2 recombinant protein (Position: E201-A651).
-
亚型
- IgG
-
-
-
-
应用备注
-
Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Fujino, T., Kondo, J., Ishikawa, M., Morikawa, K., Yamamoto, T. T. Acetyl-CoA synthetase 2, a mitochondrial matrix enzyme involved in the oxidation of acetate. J. Biol. Chem. 276: 11420-11426, 2001. 2. Luong, A., Hannah, V. C., Brown, M. S., Goldstein, J. L. Molecular characterization of human acetyl-CoA synthetase, an enzyme regulated by sterol regulatory element-binding proteins. J. Biol. Chem. 275: 26458-26466, 2000. 3. Mews, P., Donahue, G., Drake, A. M., Luczak, V., Abel, T., Berger, S. L. Acetyl-CoA synthetase regulates histone acetylation and hippocampal memory. Nature 546: 381-386, 2017. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- ACSS2 (Acyl-CoA Synthetase Short-Chain Family Member 2 (ACSS2))
-
别名
- ACSS2
-
背景
-
Synonyms: E3 SUMO-protein ligase PIAS3, Protein inhibitor of activated STAT protein 3, PIAS3
Tissue Specificity: Widely expressed.
Background: Acyl-coenzyme A synthetase short-chain family member 2 is an enzyme that in humans is encoded by the ACSS2 gene. This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants.
-
分子量
- 79 kDa
-
基因ID
- 55902
抗原
-