14-3-3 Pan (AA 174-245) 抗体
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北京 101111
Quick Overview for 14-3-3 Pan (AA 174-245) 抗体 (ABIN726710)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 174-245
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交叉反应
- 人, 小鼠, 大鼠, Saccharomyces cerevisiae
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预测反应
- Sheep,Drosophila
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human 14-3-3
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亚型
- IgG
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anti-14-3-3 Pan antibody
适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal 3C8 unconjugated
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应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- 14-3-3 Pan
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别名
- 14-3-3 Alpha + Beta + Gamma + Delta + Epsilon
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背景
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Synonyms: HS1, GW128, YWHAA, KCIP-1, HEL-S-1, 14-3-3 protein beta/alpha, Protein 154, Protein kinase C inhibitor protein 1, YWHAB
Background: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2.
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基因ID
- 7529
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UniProt
- P31946
抗原
-
