SCFD2 抗体 (AA 20-585)
Quick Overview for SCFD2 抗体 (AA 20-585) (ABIN7600557)
抗原
See all SCFD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-585
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原理
- Anti-SCFD2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SCFD2 Antibody Picoband® (ABIN7600557). Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SCFD2 recombinant protein (Position: K20-H585).
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亚型
- IgG
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anti-Sec1 Family Domain Containing 2 (SCFD2) (AA 255-470) antibody
SCFD2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sec1 Family Domain Containing 2 (SCFD2) (AA 1-684) antibodySCFD2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sec1 Family Domain Containing 2 (SCFD2) (AA 219-268) antibodySCFD2 适用: 人, 小鼠, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Sec1 Family Domain Containing 2 (SCFD2) (Middle Region) antibodySCFD2 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Mitobe, Y. , Iino, K. , Takayama, K. , Ikeda, K. , Suzuki, T. , & Aogi, K. , et al. (2020). Psf promotes er-positive breast cancer progression via posttranscriptional regulation of esr1 and scfd2. Cancer research, 80(11), 2230-2242. 2. Takeiwa, T. , Ikeda, K. , Suzuki, T. , Sato, W. , Iino, K. , & Mitobe, Y. , et al. (2022). Pspc1 is a potential prognostic marker for hormone-dependent breast cancer patients and modulates rna processing of esr1 and scfd2. Scientific reports, 12(1), 9495. 3. (2010). Genome-wide association identifies atoh7 as a major gene determining human optic disc size. Human Molecular Genetics, 19(13), 2716. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SCFD2 (Sec1 Family Domain Containing 2 (SCFD2))
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别名
- SCFD2
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背景
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Synonyms: Kelch repeat and BTB domain-containing protein 2, BTB and kelch domain-containing protein 1, KBTBD2, BKLHD1, KIAA1489
Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.
Background: SCFD2 (sec1 family domain containing 2), also known as STXBP1L1 (syntaxinbinding protein 1-like 1), is a 684 amino acid protein suggested to play a role in protein transport. Existing as two alternatively spliced isoforms, SCFD2 is a member of the STXBP/unc-18/SEC1 family and is encoded by a gene that maps to human chromosome 4q12. Chromosome 4 represents approximately 6 % of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease
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分子量
- 75 kDa
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基因ID
- 152579
抗原
-
