NFE2 抗体 (AA 20-373)
Quick Overview for NFE2 抗体 (AA 20-373) (ABIN7600550)
抗原
See all NFE2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-373
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原理
- Anti-NFE2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-NFE2 Antibody Picoband® (ABIN7600550). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NFE2 recombinant protein (Position: E20-D373).
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亚型
- IgG
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anti-Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2) (AA 1-373) antibody
NFE2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C6 unconjugated
anti-Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2) (Center) antibodyNFE2 适用: 人, 小鼠 WB, IF, IP, ICC, ChIP-seq 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2) (N-Term) antibodyNFE2 适用: 人, 小鼠, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2) (AA 108-157) antibodyNFE2 适用: 人, 马, 犬, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bannerman, R. M., Edwards, J. A., Kreimer-Birnbaum, M., McFarland, E., Russell, E. S. Hereditary microcytic anaemia in the mouse, studies in iron distribution and metabolism. Brit. J. Haemat. 23: 235-245, 1972. 2. Chan, J. Y., Cheung, M.-C., Moi, P., Chan, K., Kan, Y. W. Chromosomal localization of the human NF-E2 family of bZIP transcription factors by fluorescence in situ hybridization. Hum. Genet. 95: 265-269, 1995. 3. Chan, J. Y., Han, X.-L., Kan, Y. W. Isolation of cDNA encoding the human NF-E2 protein. Proc. Nat. Acad. Sci. 90: 11366-11370, 1993. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))
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别名
- NFE2
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背景
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Synonyms: NAD-dependent protein lipoamidase sirtuin-4, mitochondrial, NAD-dependent ADP-ribosyltransferase sirtuin-4, NAD-dependent protein deacetylase sirtuin-4, Regulatory protein SIR2 homolog 4, SIR2-like protein 4, SIRT4, SIR2L4
Tissue Specificity: Detected in vascular smooth muscle and striated muscle. Detected in insulin-producing beta-cells in pancreas islets of Langerhans (at protein level). Widely expressed. Weakly expressed in leukocytes and fetal thymus.
Background: Transcription factor NF-E2 45 kDa subunit is a protein that in humans is encoded by the NFE2 gene. Enables several functions, including WW domain binding activity, identical protein binding activity, and protein N-terminus binding activity. Contributes to cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including labyrinthine layer blood vessel development, negative regulation of bone mineralization, and negative regulation of syncytium formation by plasma membrane fusion. Part of protein-DNA complex.
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分子量
- 41 kDa
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基因ID
- 4778
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UniProt
- Q16621
抗原
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