TARBP2 抗体 (AA 20-366)
Quick Overview for TARBP2 抗体 (AA 20-366) (ABIN7600548)
抗原
See all TARBP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-366
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原理
- Anti-TRBP/TARBP2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-TRBP/TARBP2 Antibody Picoband® (ABIN7600548). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TRBP/TARBP2 recombinant protein (Position: E20-K366).
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亚型
- IgG
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anti-TAR (HIV-1) RNA Binding Protein 2 (TARBP2) antibody
TARBP2 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-TAR (HIV-1) RNA Binding Protein 2 (TARBP2) (AA 141-250) antibodyTARBP2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1D9 unconjugated
anti-TAR (HIV-1) RNA Binding Protein 2 (TARBP2) (AA 141-250) antibodyTARBP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H1 unconjugated
anti-TAR (HIV-1) RNA Binding Protein 2 (TARBP2) (AA 1-366) antibodyTARBP2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-TAR (HIV-1) RNA Binding Protein 2 (TARBP2) (AA 1-366) antibodyTARBP2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1G6 unconjugated
anti-TAR (HIV-1) RNA Binding Protein 2 (TARBP2) (AA 340-390) antibodyTARBP2 适用: 人, 小鼠, 大鼠, 马, 猴, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TAR (HIV-1) RNA Binding Protein 2 (TARBP2) (AA 1-366) antibodyTARBP2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TAR (HIV-1) RNA Binding Protein 2 (TARBP2) (AA 60-89), (N-Term) antibodyTARBP2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33928 unconjugated
anti-TAR (HIV-1) RNA Binding Protein 2 (TARBP2) (AA 1-366) antibodyTARBP2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TAR (HIV-1) RNA Binding Protein 2 (TARBP2) (AA 1-366) antibodyTARBP2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10^6 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chendrimada, T. P., Gregory, R. I., Kumaraswamy, E., Norman, J., Cooch, N., Nishikura, K., Shiekhattar, R. TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. (Letter) Nature 436: 740-744, 2005. 2. Garre, P., Perez-Segura, P., Diaz-Rubio, E., Caldes, T., de la Hoya, M. Reassessing the TARBP2 mutation rate in hereditary nonpolyposis colorectal cancer. (Letter) Nature Genet. 42: 817-818, 2010. 3. Gatignol, A., Buckler-White, A., Berkhout, B., Jeang, K. T. Characterization of a human TAR RNA-binding protein that activates the HIV-1 LTR. Science 251: 1597-1600, 1991. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))
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别名
- TARBP2
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背景
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Synonyms: Gastrin/cholecystokinin type B receptor, CCK-B receptor, CCK-BR, Cholecystokinin-2 receptor, CCK2-R, CCKBR, CCKRB
Tissue Specificity: Isoform 1 is expressed in brain, pancreas, stomach, the colon cancer cell line LoVo and the T-lymphoblastoma Jurkat, but not in heart, placenta, liver, lung, skeletal muscle, kidney or the stomach cancer cell line AGS. Expressed at high levels in the small cell lung cancer cell line NCI-H510, at lower levels in NCI-H345, NCI-H69 and GLC-28 cell lines, not expressed in GLC-19 cell line. Within the stomach, expressed at high levels in the mucosa of the gastric fundus and at low levels in the antrum and duodenum. Isoform 2 is present in pancreatic cancer cells and colorectal cancer cells, but not in normal pancreas or colonic mucosa. Isoform 3 is expressed in brain, pancreas, stomach, the stomach cancer cell line AGS and the colon cancer cell line LoVo.
Background: RISC-loading complex subunit TARBP2 is a protein that in humans is encoded by the TARBP2 gene. HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene.
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分子量
- 44 kDa
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基因ID
- 6895
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UniProt
- Q15633
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途径
- Regulatory RNA Pathways, Ribonucleoprotein Complex Subunit Organization
抗原
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