MAD2L1BP 抗体 (AA 20-274)
Quick Overview for MAD2L1BP 抗体 (AA 20-274) (ABIN7600535)
抗原
See all MAD2L1BP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-274
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原理
- Anti-MAD2L1BP Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MAD2L1BP Antibody Picoband® (ABIN7600535). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MAD2L1BP recombinant protein (Position: Y20-E274).
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亚型
- IgG
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anti-MAD2L1 Binding Protein (MAD2L1BP) (AA 1-274) antibody
MAD2L1BP 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4G11 unconjugated
anti-MAD2L1 Binding Protein (MAD2L1BP) antibodyMAD2L1BP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-MAD2L1 Binding Protein (MAD2L1BP) (AA 1-306) antibodyMAD2L1BP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-MAD2L1 Binding Protein (MAD2L1BP) (AA 1-274) antibodyMAD2L1BP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-MAD2L1 Binding Protein (MAD2L1BP) (AA 1-306) antibodyMAD2L1BP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-MAD2L1 Binding Protein (MAD2L1BP) (N-Term) antibodyMAD2L1BP 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MAD2L1 Binding Protein (MAD2L1BP) antibodyMAD2L1BP 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-MAD2L1 Binding Protein (MAD2L1BP) (N-Term) antibodyMAD2L1BP 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-MAD2L1 Binding Protein (MAD2L1BP) (AA 1-274) antibodyMAD2L1BP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-MAD2L1 Binding Protein (MAD2L1BP) (AA 171-274) antibodyMAD2L1BP 适用: 人 ELISA, IP 宿主: 小鼠 Monoclonal 4B9 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Alfieri, C., Chang, L., Barford, D. Mechanism for remodelling of the cell cycle checkpoint protein MAD2 by the ATPase TRIP13. Nature 559: 274-278, 2018. 2. Date, D. A., Burrows, A. C., Venere, M., Jackson, M. W., Summers, M. K. Coordinated regulation of p31(Comet) and Mad2 expression is required for cellular proliferation. Cell Cycle 12: 3824-3832, 2013. 3. Eytan, E., Wang, K., Miniowitz-Shemtov, S., Sitry-Shevah, D., Kaisari, S., Yen, T. J., Liu, S.-T., Hershko, A. Disassembly of mitotic checkpoint complexes by the joint action of the AAA-ATPase TRIP13 and p13(comet). Proc. Nat. Acad. Sci. 111: 12019-12024, 2014. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MAD2L1BP (MAD2L1 Binding Protein (MAD2L1BP))
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别名
- MAD2L1BP
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背景
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Synonyms: Intraflagellar transport protein 88 homolog, Recessive polycystic kidney disease protein Tg737 homolog, Tetratricopeptide repeat protein 10, TPR repeat protein 10, IFT88, TG737, TTC10
Tissue Specificity: Expressed in the heart, brain, liver, lung, kidney, skeletal muscle and pancreas.
Background: MAD2L1-binding protein is a protein that in humans is encoded by the MAD2L1BP gene. The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
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分子量
- 37 kDa
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基因ID
- 9587
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UniProt
- Q15013
抗原
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