CD103 抗体 (AA 20-1061)
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Quick Overview for CD103 抗体 (AA 20-1061) (ABIN7600516)
抗原
See all CD103 (ITGAE) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-1061
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原理
- Anti-CD103/Itgae Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-/Itgae Antibody (ABIN7600516). Tested in ELISA, IHC applications. This antibody reacts with Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse CD103/Itgae recombinant protein (Position: F20-E1061).
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亚型
- IgG
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应用备注
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Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- CD103 (ITGAE) (Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE))
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别名
- Itgae
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背景
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Synonyms: Ribosome-binding protein 1, 180 kDa ribosome receptor homolog, RRp, ES/130-related protein, Ribosome receptor protein, RRBP1, KIAA1398
Tissue Specificity: Expressed in kidney.
Background: ITGAE(INTEGRIN, ALPHA-E), also known as CD103, is an integrin protein that in human is encoded by the ITGAE gene. The ITGAE gene is mapped to chromosome 17p13 by inclusion within a BAC contig. ITGAE is expressed widely on intraepithelial lymphocyte(IEL) T cells(both alphabeta T cells and gammadelta T cells) and on some peripheral regulatory T cells(Tregs) which is important for decreasing the immune response and appears to play a crucial role in the prevention of autoimmune diseases. ITGAE shares overall homology with other alpha integrins but has a unique 55-amino acid "extra" region located just N-terminal to the I domain that contains 18 consecutive charged residues and a proteolytic cleavage site.
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分子量
- 81 kDa
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基因ID
- 16407
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UniProt
- Q60677
抗原
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