GCHFR 抗体 (AA 2-84)
Quick Overview for GCHFR 抗体 (AA 2-84) (ABIN7600511)
抗原
See all GCHFR 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 2-84
-
原理
- Anti-GCHFR Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-GCHFR Antibody Picoband® (ABIN7600511). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human GCHFR recombinant protein (Position: P2-E84).
-
亚型
- IgG
-
-
anti-GTP Cyclohydrolase I Feedback Regulator (GCHFR) antibody
Microarray verified GCHFR 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB689354 unconjugated
anti-GTP Cyclohydrolase I Feedback Regulator (GCHFR) (AA 11-55) antibodyGCHFR 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GTP Cyclohydrolase I Feedback Regulator (GCHFR) antibodyMicroarray verified GCHFR 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB991590 unconjugated
anti-GTP Cyclohydrolase I Feedback Regulator (GCHFR) antibodyMicroarray verified GCHFR 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB694198 unconjugated
anti-GTP Cyclohydrolase I Feedback Regulator (GCHFR) antibodyMicroarray verified GCHFR 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB17092 unconjugated
anti-GTP Cyclohydrolase I Feedback Regulator (GCHFR) (AA 1-84) antibodyGCHFR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-GTP Cyclohydrolase I Feedback Regulator (GCHFR) (AA 1-84) antibodyGCHFR 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 4G6 unconjugated
anti-GTP Cyclohydrolase I Feedback Regulator (GCHFR) (N-Term) antibodyGCHFR 适用: 人, 小鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-GTP Cyclohydrolase I Feedback Regulator (GCHFR) (N-Term) antibodyGCHFR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Milstien, S., Jaffe, H., Kowlessur, D., Bonner, T. I. Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP. J. Biol. Chem. 271: 19743-19751, 1996 -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.005 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- GCHFR (GTP Cyclohydrolase I Feedback Regulator (GCHFR))
-
别名
- GCHFR
-
背景
-
Synonyms: Zinc finger protein 42 homolog, Zfp-42, Reduced expression protein 1, REX-1, hREX-1, Zinc finger protein 754, ZFP42, REX1, ZNF754
Tissue Specificity: Expressed in kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells (at protein level). Expressed in malignant kidney and several carcinoma cell lines (at protein level). Expressed in embryonic stem cells, kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells. Expressed in embryonal carcinomas, seminomas, malignant kidney and several carcinoma cell lines.
Background: GTP cyclohydrolase 1 feedback regulatory protein is an enzyme that in humans is encoded by the GCHFR gene. GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.
-
分子量
- 12 kDa
-
基因ID
- 2644
-
UniProt
- P30047
抗原
-
