EGR1 抗体 (AA 2-38)
Quick Overview for EGR1 抗体 (AA 2-38) (ABIN7600495)
抗原
See all EGR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-38
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原理
- Anti-EGR1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-EGR1 Antibody Picoband® (ABIN7600495). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human EGR1 recombinant protein (Position: A2-M38).
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亚型
- IgG
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anti-Early Growth Response 1 (EGR1) (AA 444-543) antibody
EGR1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 6E8 unconjugated
anti-Early Growth Response 1 (EGR1) (AA 444-543) antibodyEGR1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Early Growth Response 1 (EGR1) (AA 23-43), (N-Term) antibodyEGR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Early Growth Response 1 (EGR1) (AA 9-37) antibodyEGR1 适用: 人, 小鼠 WB, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Early Growth Response 1 (EGR1) (N-Term) antibodyEGR1 适用: 人, 小鼠, 大鼠, 马, Cow, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Early Growth Response 1 (EGR1) (AA 9-37), (N-Term) antibodyEGR1 适用: 人, 小鼠 WB, FACS, IF 宿主: 兔 Polyclonal RB19179 unconjugated
anti-Early Growth Response 1 (EGR1) (AA 401-453) antibodyEGR1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Early Growth Response 1 (EGR1) (AA 282-433) antibodyEGR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Early Growth Response 1 (EGR1) (AA 211-320) antibodyEGR1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F5 unconjugated
anti-Early Growth Response 1 (EGR1) (AA 444-543) antibodyEGR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C7 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Das, A., Chendil, D., Dey, S., Mohiuddin, M., Mohiuddin, M., Milbrandt, J., Rangnekar, V. M., Ahmed, M. M. Ionizing radiation down-regulates p53 protein in primary Egr-1(-/-) mouse embryonic fibroblast cells causing enhanced resistance to apoptosis. J. Biol. Chem. 276: 3279-3286, 2001. 2. Joslin, J. M., Fernald, A. A., Tennant, T. R., Davis, E. M., Kogan, S. C., Anastasi, J., Crispino, J. D., Le Beau, M. M. Haploinsufficiency of EGR1, a candidate gene in the del(5q), leads to the development of myeloid disorders. Blood 110: 719-726, 2007. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- EGR1 (Early Growth Response 1 (EGR1))
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别名
- EGR1
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背景
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Synonyms: Early growth response protein 1
Tissue Specificity: Detected in neutrophils (at protein level).
Background: Earlu growth response protein 1, also known as ZIF268 or NGFIA, is a protein that in humans is encoded by the EGR1 gene. The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. This gene is mapped to 5q31.2. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. It has a distinct pattern of expression in the brain, and its induction has been shown to be associated with neuronal activity. Several studies suggest it has a role in neuronal plasticity.
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分子量
- 60 kDa
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基因ID
- 1958
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UniProt
- P18146
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途径
- Regulation of Carbohydrate Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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