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Transglutaminase 2 抗体 (AA 2-37)

This anti-Transglutaminase 2 antibody is a 兔 多克隆 antibody detecting Transglutaminase 2 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7600494
发货至: 中国

Quick Overview for Transglutaminase 2 抗体 (AA 2-37) (ABIN7600494)

抗原

See all Transglutaminase 2 (TGM2) 抗体
Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

适用

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宿主

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克隆类型

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多克隆

标记

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This Transglutaminase 2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
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    AA 2-37

    原理

    Anti-TGM2 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-TGM2 Antibody Picoband® (ABIN7600494). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human TGM2 recombinant protein (Position: A2-Q37).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Antonyak, M. A., Jansen, J. M., Miller, A. M., Ly, T. K., Endo, M., Cerione, R. A. Two isoforms of tissue transglutaminase mediate opposing cellular fates. Proc. Nat. Acad. Sci. 103: 18609-18614, 2006. 2. Mastroberardino, P. G., Iannicola, C., Nardacci, R., Bernassola, F., de Laurenzi, V., Melino, G., Moreno, S., Pavone, F., Oliverio, S., Fesus, L., Piacentini, M. 'Tissue' transglutaminase ablation reduces neuronal death and prolongs survival in a mouse model of Huntington's disease. Cell Death Differ. 9: 873-880, 2002. 3. Priglinger, S. G., May, C. A., Neubauer, A. S., Alge, C. S., Schoenfeld, C.-L., Kampik, A., Welge-Lussen, U. Tissue transglutaminase as a modifying enzyme of the extracellular matrix in PVR membranes. Invest. Ophthal. Vis. Sci. 44: 355-364, 2003.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

    别名

    TGM2

    背景

    Synonyms: Cytokine receptor common subunit beta, GM-CSF/IL-3/IL-5 receptor common beta subunit, CD131, Csf2rb, Aic2b, Csf2rb1, Il3rb1

    Tissue Specificity: Broadly expressed with higher expression in heart.

    Background: Tissue transglutaminase, also called TGC, is a 78- kDa, calcium dependent enzyme of the protein-glutamine gamma-glutamyltransferases family. By fluorescence in situ hybridization (FISH), this gene is mapped in 20q11.23. Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease.

    分子量

    80 kDa

    基因ID

    7052

    UniProt

    P21980

    途径

    Tube Formation, Thromboxane A2 Receptor Signaling
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