HSC70 Interacting Protein HIP 抗体 (AA 2-369)
Quick Overview for HSC70 Interacting Protein HIP 抗体 (AA 2-369) (ABIN7600493)
抗原
See all HSC70 Interacting Protein HIP (ST13) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-369
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原理
- Anti-ST13 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-ST13 Antibody Picoband® (ABIN7600493). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ST13 recombinant protein (Position: D2-A369).
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亚型
- IgG
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anti-Suppression of Tumorigenicity 13 (ST13) antibody
ST13 适用: 人, 猴 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 3B10 unconjugated
anti-Suppression of Tumorigenicity 13 (ST13) (AA 1-369) antibodyST13 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Suppression of Tumorigenicity 13 (ST13) (AA 1-58) antibodyST13 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B2 unconjugated
anti-Suppression of Tumorigenicity 13 (ST13) antibodyST13 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Suppression of Tumorigenicity 13 (ST13) (AA 41-90) antibodyST13 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Suppression of Tumorigenicity 13 (ST13) (AA 166-369) antibodyST13 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Suppression of Tumorigenicity 13 (ST13) (AA 1-369) antibodyST13 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Suppression of Tumorigenicity 13 (ST13) antibodyST13 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Suppression of Tumorigenicity 13 (ST13) (AA 50-80) antibodyST13 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB2078 unconjugated
anti-Suppression of Tumorigenicity 13 (ST13) (N-Term) antibodyST13 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Cao, J., Cai, X., Zheng, L., Geng, L., Shi, Z., Pao, C. C., Zheng, S. Characterization of colorectal-cancer-related cDNA clones obtained by subtractive hybridization screening. J. Cancer Res. Clin. Oncol. 123: 447-451, 1997. 2. Hohfeld, J., Minami, Y., Hartl, F.-U. Hip, a novel cochaperone involved in the eukaryotic Hsc70/Hsp40 reaction cycle. Cell 83: 589-598, 1995. 3. Howarth, J. L., Glover, C. P. J., Uney, J. B. HSP70 interacting protein prevents the accumulation of inclusions in polyglutamine disease. J. Neurochem. 108: 945-951, 2009. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))
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别名
- ST13
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背景
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Synonyms: N-alpha-acetyltransferase 15, NatA auxiliary subunit,Gastric cancer antigen Ga19,N-terminal acetyltransferase,NMDA receptor-regulated protein 1,Protein tubedown-1,Tbdn100,NAA15,GA19, NARG1, NATH, TBDN100,
Tissue Specificity: Expressed at high levels in testis and in ocular endothelial cells. Also found in brain (corpus callosum), heart, colon, bone marrow and at lower levels in most adult tissues, including thyroid, liver, pancreas, mammary and salivary glands, lung, ovary, urogenital system and upper gastrointestinal tract. Overexpressed in gastric cancer, in papillary thyroid carcinomas and in a Burkitt lymphoma cell line (Daudi). Specifically suppressed in abnormal proliferating blood vessels in eyes of patients with proliferative diabetic retinopathy. .
Background: Hsc70-interacting protein also known as suppression of tumorigenicity 13 (ST13) is a protein that in humans is encoded by the ST13 gene. The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that it is a candidate tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding different isoforms.
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分子量
- 45-54 kDa
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基因ID
- 6767
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UniProt
- P50502
抗原
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