MVP 抗体 (AA 2-259) (DyLight 488)
Quick Overview for MVP 抗体 (AA 2-259) (DyLight 488) (ABIN7600482)
抗原
See all MVP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 2-259
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原理
- Anti-Human MVP DyLight® 488 conjugated Antibody(monoclonal, 8B12)
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Human MVP DyLight® 488 conjugated Antibody (monoclonal, 8B12) -Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.
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免疫原
- E. coli-derived human MVP recombinant protein (Position: A2-H259).
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亚型
- IgG2a
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应用备注
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Flow Cytometry (Fixed), 1-3 μg/1x106 cells, human
1. "Entrez Gene: MVP major vault protein". 2. Izquierdo MA, Scheffer GL, Flens MJ, Schroeijers AB, van der Valk P, Scheper RJ (Jun 1996). "Major vault protein LRP-related multidrug resistance". European Journal of Cancer. 32A (6): 979-84. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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- MVP (Major Vault Protein (MVP))
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别名
- MVP
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背景
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Synonyms: Major vault protein, MVP, Lung resistance-related protein, MVP, LRP
Background: Major vault protein is a protein that in humans is encoded by the MVP gene. This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.
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分子量
- 39 kDa
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基因ID
- 9961
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UniProt
- Q14764
抗原
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