PPFIA1 抗体 (AA 198-1202)
Quick Overview for PPFIA1 抗体 (AA 198-1202) (ABIN7600454)
抗原
See all PPFIA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 198-1202
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原理
- Anti-PPFIA1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PPFIA1 Antibody Picoband® (ABIN7600454). Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PPFIA1 recombinant protein (Position: A198-C1202).
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亚型
- IgG
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anti-Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1) (N-Term) antibody
PPFIA1 适用: 人, 小鼠 WB, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1) (C-Term) antibodyPPFIA1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1) (AA 660-800) antibodyPPFIA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1) (AA 1-250) antibodyPPFIA1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1) antibodyPPFIA1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1) (AA 660-800) antibodyPPFIA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hoogenraad, C. C., Feliu-Mojer, M. I., Spangler, S. A., Milstein, A. D., Dunah, A. W., Hung, A. Y., Sheng, M. Liprin-alpha-1 degradation by calcium/calmodulin-dependent protein kinase II regulates LAR receptor tyrosine phosphatase distribution and dendrite development. Dev. Cell 12: 587-602, 2007. [PubMed: 17419996, related citations] [Full Text] 2. Streuli, M. The LAR transmembrane protein tyrosine phosphatase and a coiled-coil LAR-interacting protein co-localize at focal adhesions. EMBO J. 14: 2827-2838, 1995. 3. Serra-Pages, C., Medley, Q. G., Tang, M., Hart, A., Streuli, M. Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins. J. Biol. Chem. 273: 15611-15620, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PPFIA1 (Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1))
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别名
- PPFIA1
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背景
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Synonyms: Activator of 90 kDa heat shock protein ATPase homolog 1, AHA1, p38, AHSA1, C14orf3, HSPC322
Tissue Specificity: Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.
Background: Liprin-alpha-1 is a protein that in humans is encoded by the PPFIA1 gene. The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described.
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分子量
- 160 kDa
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基因ID
- 8500
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UniProt
- Q13136
抗原
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