SEC23A 抗体 (AA 190-579)
Quick Overview for SEC23A 抗体 (AA 190-579) (ABIN7600428)
抗原
See all SEC23A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 190-579
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原理
- Anti-SEC23A Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SEC23A Antibody Picoband® (ABIN7600428). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SEC23A recombinant protein (Position: R190-Q579).
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亚型
- IgG
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anti-Sec23 Homolog A (SEC23A) (AA 424-569) antibody
SEC23A 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sec23 Homolog A (SEC23A) antibodySEC23A 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Sec23 Homolog A (SEC23A) (Internal Region) antibodyVerified SEC23A 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Sec23 Homolog A (SEC23A) (AA 1-150) antibodySEC23A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Boyadjiev, S. A., Fromme, J. C., Ben, J., Chong, S. S., Nauta, C., Hur, D. J., Zhang, G., Hamamoto, S., Schekman, R., Ravazzola, M., Orci, L., Eyaid, W. Cranio-lenticulo-sutural dysplasia is caused by a SEC23A mutation leading to abnormal endoplasmic-reticulum-to-Golgi trafficking. Nature Genet. 38: 1192-1197, 2006. 2. Boyadjiev, S. A., Justice, C. M., Eyaid, W., McKusick, V. A., Lachman, R. S., Chowdry, A. B., Jabak, M., Zwaan, J., Wilson, A. F., Jabs, E. W. A novel dysmorphic syndrome with open calvarial sutures and sutural cataracts maps to chromosome 14q13-q21. Hum. Genet. 113: 1-9, 2003. 3. Boyadjiev, S. A., Kim, S.-D., Hata, A., Haldeman-Englert, C., Zackai, E. H., Naydenov, C., Hamamoto, S., Schekman, R. W., Kim, J. Cranio-lenticulo-sutural dysplasia associated with defects in collagen secretion. Clin. Genet. 80: 169-176, 2011. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SEC23A (Sec23 Homolog A (SEC23A))
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别名
- SEC23A
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背景
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Synonyms: E3 ISG15--protein ligase HERC5, Cyclin-E-binding protein 1, HECT domain and RCC1-like domain-containing protein 5, HERC5, CEB1, CEBP1
Tissue Specificity: Expressed in testis and to a lesser degree in brain, ovary and placenta. Found in most tissues at low levels.
Background: Sec23 homolog A (S. cerevisiae), also known as SEC23A, is a protein which in humans is encoded by the SEC23A gene. The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family. It is part of a protein complex and found in the ribosome-free transitional face of the endoplasmic reticulum (ER) and associated vesicles. This protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The encoded protein is suggested to play a role in the ER-Golgi protein trafficking.
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分子量
- 86 kDa
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基因ID
- 10484
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UniProt
- Q15436
抗原
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