OSCAR 抗体 (AA 19-282)
Quick Overview for OSCAR 抗体 (AA 19-282) (ABIN7600409)
抗原
See all OSCAR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 19-282
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原理
- Anti-OSCAR Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-OSCAR Antibody Picoband® (ABIN7600409). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human OSCAR recombinant protein (Position: D19-V282). Human OSCAR shares 77.3% amino acid (aa) sequence identity with mouse OSCAR.
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亚型
- IgG
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anti-Osteoclast Associated Receptor (OSCAR) antibody
OSCAR 适用: 人 WB 宿主: 小鼠 Monoclonal C2 unconjugated
anti-Osteoclast Associated Receptor (OSCAR) (AA 265-279) antibodyOSCAR 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Osteoclast Associated Receptor (OSCAR) (AA 205-231) antibodyOSCAR 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL
1. Barrow, A. D., Palarasah, Y., Bugatti, M., Holehouse, A. S., Byers, D. E., Holtzman, M. J., Vermi, W., Skjodt, K., Crouch, E., Colonna, M. OSCAR is a receptor for surfactant protein D that activates TNF-alpha release from human CCR2+ inflammatory monocytes. J. Immun. 194: 3317-3326, 2015. 2. Kim, K., Kim, J. H., Lee, J., Jin, H.-M., Lee, S.-H., Fisher, D. E., Kook, H., Kim, K. K., Choi, Y., Kim, N. Nuclear factor of activated T cells c1 induces osteoclast-associated receptor gene expression during tumor necrosis factor-related activation-induced cytokine-mediated osteoclastogenesis. J. Biol. Chem. 280: 35209-35216, 2005. 3. Kim, N., Takami, M., Rho, J., Josien, R., Choi, Y. A novel member of the leukocyte receptor complex regulates osteoclast differentiation. J. Exp. Med. 195: 201-209, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- OSCAR (Osteoclast Associated Receptor (OSCAR))
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别名
- OSCAR
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背景
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Synonyms: OSCAR, Osteoclast-associated immunoglobulin-like receptor, Osteoclast-associated receptor, hOSCAR, Polymeric immunoglobulin receptor 3, PIgR-3, PIgR3, Poly-Ig receptor 3
Background: Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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分子量
- 30 kDa
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基因ID
- 126014
抗原
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