STAMBPL1 抗体 (AA 187-436)
Quick Overview for STAMBPL1 抗体 (AA 187-436) (ABIN7600389)
抗原
See all STAMBPL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 187-436
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原理
- Anti-AMSH-LP/STAMBPL1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-AMSH-LP/STAMBPL1 Antibody Picoband® (ABIN7600389). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human AMSH-LP/STAMBPL1 recombinant protein (Position: Q187-R436).
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亚型
- IgG
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anti-STAM Binding Protein-Like 1 (STAMBPL1) (AA 135-163) antibody
STAMBPL1 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26763 unconjugated
anti-STAM Binding Protein-Like 1 (STAMBPL1) (N-Term) antibodySTAMBPL1 适用: 人, 小鼠, 豚鼠, 马, 兔, 大鼠, 犬, Pig, Bat, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-STAM Binding Protein-Like 1 (STAMBPL1) (AA 120-250) antibodySTAMBPL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-STAM Binding Protein-Like 1 (STAMBPL1) antibodySTAMBPL1 适用: 人 DB, ICC 宿主: 小鼠 Monoclonal 2020C4a unconjugated
anti-STAM Binding Protein-Like 1 (STAMBPL1) (N-Term) antibodySTAMBPL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-STAM Binding Protein-Like 1 (STAMBPL1) (N-Term) antibodySTAMBPL1 适用: 人, 小鼠, 豚鼠, 马, 兔, 大鼠, 犬, Cow, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Kikuchi, K., Ishii, N., Asao, H., Sugamura, K. Identification of AMSH-LP containing a Jab1/MPN domain metalloenzyme motif. Biochem. Biophys. Res. Commun. 306: 637-643, 2003. 2. Kitajima, K., Matsumoto, K., Tahara, M., Takahashi, H., Nakamura, T., Nakamura, T. A newly identified AMSH-family protein is specifically expressed in haploid stages of testicular germ cells. Biochem. Biophys. Res. Commun. 309: 135-142, 2003. 3. Nagase, T., Kikuno, R., Ishikawa, K., Hirosawa, M., Ohara, O. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 7: 65-73, 2000. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- STAMBPL1 (STAM Binding Protein-Like 1 (STAMBPL1))
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别名
- STAMBPL1
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背景
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Synonyms: Interleukin-36 alpha, FIL1 epsilon, Interleukin-1 epsilon, IL-1 epsilon, Interleukin-1 family member 6, IL-1F6, IL36A, FIL1E, IL1E, IL1F6
Tissue Specificity: Expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. Predominantly expressed in skin keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Increased in lesional psoriasis skin.
Background: STAMBPL1 (STAM-binding protein-like 1), also known as AMSH-FP, AMSH-LP (associated molecule with the SH3 domain of STAM like protein) or ALMa, is a 436 amino acid protein that belongs to the peptidase M67C family, contains one MPN domain and a JAMM motif that is essential for protease activity. Existing as two alternatively spliced isoforms, STAMBPL1 is a ubiquitously expressed protein that binds two zinc ions per subunit and acts as a zinc metalloprotease that specifically cleaves Lys-63-linked polyubiquitin chains. The gene that encodes STAMBPL1 maps to human chromosome 10q23.31. Chromosome 10 contains over 800 genes and 135 million nucleotides, making up nearly 4.5 % of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10.
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分子量
- 50 kDa
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基因ID
- 57559
抗原
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