SOX2 抗体 (AA 185-208)
Quick Overview for SOX2 抗体 (AA 185-208) (ABIN7600382)
抗原
See all SOX2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 185-208
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原理
- Anti-SOX2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SOX2 Antibody Picoband® (ABIN7600382). Tested in ELISA, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SOX2 recombinant protein (Position: G185-N208).
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亚型
- IgG
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anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody
KO Validated SOX2 适用: 人 WB, IF, FACS, ICC, IHC (p), IP, IHC (fro), CUT&RUN 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 227-317) antibodySOX2 适用: 人, 小鼠, 大鼠, 山羊 WB, ELISA, FACS, ICC, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-140) antibodySOX2 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-317) antibodySOX2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 176-305) antibodySOX2 适用: 人, 小鼠 WB, ELISA, IHC, Coat, StM 宿主: 小鼠 Monoclonal SOX2-1791 unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (N-Term) antibodySOX2 适用: 人, 小鼠, 大鼠, 山羊, Cow, Pig, 绵羊, 斑马鱼, 马, 兔, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibodySOX2 适用: 人 ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 10F10 unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 89-119), (N-Term) antibodySOX2 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB14026 unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (Middle Region) antibodySOX2 适用: 人, 小鼠, 大鼠, 山羊, Cow, 绵羊, 斑马鱼, 马, 兔, 犬, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 89-119) antibodySOX2 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Bass, A. J., Watanabe, H., Mermel, C. H., Yu, S., Perner, S., Verhaak, R. G., Kim, S. Y., Wardwell, L., Tamayo, P., Gat-Viks, I., Ramos, A. H., Woo, M. S., and 36 others. SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nature Genet. 41: 1238-1242, 2009. 2. Masui, S., Nakatake, Y., Toyooka, Y., Shimosato, D., Yagi, R., Takahashi, K., Okochi, H., Okuda, A., Matoba, R., Sharov, A. A., Ko, M. S. H., Niwa, H. Pluripotency governed bySox2 via regulation of Oct3/4 expression in mouse embryonic stem cells. Nature Cell Biol. 9: 625-635, 2007. 3. Rizzino A (2009). "Sox2 and Oct-3/4: a versatile pair of master regulators that orchestrate the self-renewal and pluripotency of embryonic stem cells". Wiley Interdiscip Rev Syst Biol Med 1 (2): 228-36. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
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别名
- SOX2
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背景
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Synonyms: Interleukin-6, IL-6, Il6, Il-6
Tissue Specificity: Expressed in activated macrophages (at protein level).
Background: SRY(sex determining region Y)-box 2, also known as SOX2, is a transcription factor that is essential for maintaining self-renewal, or pluripotency of undifferentiated embryonic stem cells. Sox2 is a member of the Sox family of transcription factors, which have been shown to play key roles in many stages of mammalian development. This gene is mapped to 3q26.33. It is found that SOX2 can regulate OCT3/4 expression and maintains ES pluripotency through upstream transcription factors. SOX2 is identified as a lineage-survival oncogene in lung and esophageal squamous cell carcinoma. In addition to those, SOX2 has a critical role in maintenance of embryonic and neural stem cells and holds great promise in research involving induced pluripotency, an emerging and very promising field of regenerative medicine.
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分子量
- 36 kDa
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基因ID
- 6657
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UniProt
- P48431
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途径
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
抗原
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