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SOX2 抗体 (AA 185-208)

This 兔 多克隆 anti-SOX2 antibody specifically detects SOX2 in WB 和 ELISA. The antibody is reactive with 人 和 大鼠 samples.
产品编号 ABIN7600382
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for SOX2 抗体 (AA 185-208) (ABIN7600382)

抗原

See all SOX2 抗体
SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

适用

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人, 大鼠

宿主

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  • 54
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克隆类型

  • 158
  • 78
多克隆

标记

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This SOX2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 185-208

    原理

    Anti-SOX2 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-SOX2 Antibody (ABIN7600382). Tested in ELISA, WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human SOX2 recombinant protein (Position: G185-N208).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Rat
    ELISA, 0.1-0.5 μg/mL, -

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

    别名

    SOX2

    背景

    Synonyms: Interleukin-6, IL-6, Il6, Il-6

    Tissue Specificity: Expressed in activated macrophages (at protein level).

    Background: SRY(sex determining region Y)-box 2, also known as SOX2, is a transcription factor that is essential for maintaining self-renewal, or pluripotency of undifferentiated embryonic stem cells. Sox2 is a member of the Sox family of transcription factors, which have been shown to play key roles in many stages of mammalian development. This gene is mapped to 3q26.33. It is found that SOX2 can regulate OCT3/4 expression and maintains ES pluripotency through upstream transcription factors. SOX2 is identified as a lineage-survival oncogene in lung and esophageal squamous cell carcinoma. In addition to those, SOX2 has a critical role in maintenance of embryonic and neural stem cells and holds great promise in research involving induced pluripotency, an emerging and very promising field of regenerative medicine.

    分子量

    36 kDa

    基因ID

    6657

    UniProt

    P48431

    途径

    Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
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