PIGS 抗体 (AA 184-504)
Quick Overview for PIGS 抗体 (AA 184-504) (ABIN7600375)
抗原
See all PIGS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 184-504
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原理
- Anti-PIGS Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PIGS Antibody Picoband® (ABIN7600375). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PIGS recombinant protein (Position: R184-D504).
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亚型
- IgG
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anti-Phosphatidylinositol Glycan Anchor Biosynthesis, Class S (PIGS) (AA 450-518) antibody
PIGS 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-Phosphatidylinositol Glycan Anchor Biosynthesis, Class S (PIGS) (AA 40-300) antibodyPIGS 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Glycan Anchor Biosynthesis, Class S (PIGS) (AA 468-517) antibodyPIGS 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 小鸡, Hamster, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Glycan Anchor Biosynthesis, Class S (PIGS) (C-Term) antibodyPIGS 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Glycan Anchor Biosynthesis, Class S (PIGS) (AA 527-555) antibodyPIGS 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Efthymiou, S., Dutra-Clarke, M., Maroofian, R., Kaiyrzhanov, R., Scala, M., Alvi, J. R., Sultan, T., Christoforou, M., Nguyen, T. T. M., Mankad, K., Vona, B., Rad, A., Striano, P., Salpietro, V., Guillen Sacoto, M. J., Zaki, M. S., Gleeson, J. G., Campeau, P. M., Russell, B. E., Houlden, H. Expanding the phenotype of PIGS-associated early onset epileptic developmental encephalopathy. Epilepsia 62: e35-e41, 2021. 2. Gross, M. B. Personal Communication. Baltimore, Md. 7/21/2020. 3. Nguyen, T. T. M., Murakami, Y., Wigby, K. M., Baratang, N. V., Rousseau, J., St-Denis, A., Rosenfeld, J. A., Laniewski, S. C., Jones, J., Iglesias, A. D., Jones, M. C., Masser-Frye, D., and 7 others. Mutations in PIGS, encoding a GPI transamidase, cause a neurological syndrome ranging from fetal akinesia to epileptic encephalopathy. Am. J. Hum. Genet. 103: 602-611, 2018. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PIGS (Phosphatidylinositol Glycan Anchor Biosynthesis, Class S (PIGS))
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别名
- PIGS
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背景
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Synonyms: Semaphorin-3E, SEMA3E, KIAA0331, SEMAH
Tissue Specificity: Detected in the sinusoidal epithelium in the red pulp of spleen. Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon.
Background: GPI transamidase component PIG-S is an enzyme that in humans is encoded by the PIGS gene. This gene encodes a protein that is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins.
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分子量
- 65 kDa
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基因ID
- 94005
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UniProt
- Q96S52
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途径
- Inositol Metabolic Process, SARS-CoV-2 Protein Interactome
抗原
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