RBM28 抗体 (AA 18-584)
Quick Overview for RBM28 抗体 (AA 18-584) (ABIN7600351)
抗原
See all RBM28 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 18-584
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原理
- Anti-RBM28 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-RBM28 Antibody Picoband® (ABIN7600351). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RBM28 recombinant protein (Position: E18-K584).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Damianov, A., Kann, M., Lane, W. S., Bindereif, A. Human RBM28p protein is a specific nucleolar component of the spliceosomal snRNPs. Biol. Chem. 387: 1455-1460, 2006. 2. Gross, M. B. Personal Communication. Baltimore, Md. 10/30/2017. 3. Nousbeck, J., Spiegel, R., Ishida-Yamamoto, A., Indelman, M., Shani-Adir, A., Adir, N., Lipkin, E., Bercovici, S., Geiger, D., van Steensel, M. A., Steijlen, P. M., Bergman, R., Bindereif, A., Choder, M., Shalev, S., Sprecher, E. Alopecia, neurological defects, and endocrinopathy syndrome caused by decreased expression of RBM28, a nucleolar protein associated with ribosome biogenesis. Am. J. Hum. Genet. 82: 1114-1121, 2008. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- RBM28 (RNA Binding Motif Protein 28 (RBM28))
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别名
- RBM28
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背景
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Synonyms: B-cell differentiation antigen CD72, Lyb-2, CD72, CD72
Tissue Specificity: Pre-B-cells and B-cells but not terminally differentiated plasma cells.
Background: RNA-binding protein 28 is a protein that in humans is encoded by the RBM28 gene. The protein encoded by this gene is a specific nucleolar component of the spliceosomal small nuclear ribonucleoprotein (snRNP)complexes . It specifically associates with U1, U2, U4, U5, and U6 small nuclear RNAs (snRNAs), possibly coordinating their transition through the nucleolus. Mutation in this gene causes alopecia, progressive neurological defects, and endocrinopathy (ANE syndrome), a pleiotropic and clinically heterogeneous disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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分子量
- 100 kDa
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基因ID
- 55131
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途径
- SARS-CoV-2 Protein Interactome
抗原
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