Septin 4 抗体 (AA 18-451)
Quick Overview for Septin 4 抗体 (AA 18-451) (ABIN7600345)
抗原
See all Septin 4 (SEPT4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 18-451
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原理
- Anti-SEPT4/SEPTIN4 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SEPT4/SEPTIN4 Antibody Picoband® (ABIN7600345). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SEPT4/SEPTIN4 recombinant protein (Position: E18-K451).
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亚型
- IgG
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anti-Septin 4 (SEPT4) (AA 1-100) antibody
SEPT4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Septin 4 (SEPT4) (AA 33-44) antibodyVerified SEPT4 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Septin 4 (SEPT4) (AA 425-435) antibodyVerified SEPT4 适用: 人 WB, ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Septin 4 (SEPT4) (AA 1-30), (N-Term) antibodySEPT4 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB18576 unconjugated
anti-Septin 4 (SEPT4) antibodySEPT4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Septin 4 (SEPT4) (N-Term) antibodySEPT4 适用: 人, 犬, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Septin 4 (SEPT4) (AA 91-150) antibodySEPT4 适用: 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Septin 4 (SEPT4) (N-Term) antibodySEPT4 适用: 人, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Fuchs, Y., Brown, S., Gorenc, T., Rodriguez, J., Fuchs, E., Steller, H. Sept4/ARTS regulates stem cell apoptosis and skin regeneration. Science 341: 286-289, 2013. 2. Ihara, M., Kinoshita, A., Yamada, S., Tanaka, H., Tanigaki, A., Kitano, A., Goto, M., Okubo, K., Nishiyama, H., Ogawa, O., Takahashi, C., Itohara, S., Nishimune, Y., Noda, M., Kinoshita, M. Cortical organization by the septin cytoskeleton is essential for structural and mechanical integrity of mammalian spermatozoa. Dev. Cell 8: 343-352, 2005. 3. Ihara, M., Yamasaki, N., Hagiwara, A., Tanigaki, A., Kitano, A., Hikawa, R., Tomimoto, H., Noda, M., Takanashi, M., Mori, H., Hattori, N., Miyakawa, T., Kinoshita, M. Sept4, a component of presynaptic scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity. Neuron 53: 519-533, 2007. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Septin 4 (SEPT4)
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别名
- SEPTIN4
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背景
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Synonyms: Mediator of RNA polymerase II transcription subunit 20, Mediator complex subunit 20, TRF-proximal protein homolog, hTRFP, MED20, TRFP,
Tissue Specificity: Pre-B-cells and B-cells but not terminally differentiated plasma cells.
Background: Septin 4 is a protein that in humans is encoded by the gene SEPTIN4. This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct, it is localized to the mitochondria, and has a role in apoptosis and cancer.
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分子量
- 50 kDa
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基因ID
- 5414
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UniProt
- O43236
抗原
-
