SELPLG 抗体 (AA 18-397)
Quick Overview for SELPLG 抗体 (AA 18-397) (ABIN7600337)
抗原
See all SELPLG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 18-397
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原理
- Anti-PSGL-1/Selplg Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PSGL-1/Selplg Antibody Picoband® (ABIN7600337). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse PSGL-1/Selplg recombinant protein (Position: L18-P397).
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亚型
- IgG
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anti-Selectin P Ligand (SELPLG) (AA 251-350) antibody
SELPLG 适用: 人 FACS, WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Selectin P Ligand (SELPLG) antibody (PE)SELPLG 适用: 人 FACS 宿主: 小鼠 Monoclonal TC2 PE
anti-Selectin P Ligand (SELPLG) (AA 40-280) antibodySELPLG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Selectin P Ligand (SELPLG) (AA 94-345) antibodySELPLG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Selectin P Ligand (SELPLG) antibodySELPLG 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal PSGL1-1601 unconjugated
anti-Selectin P Ligand (SELPLG) (N-Term) antibodySELPLG 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Selectin P Ligand (SELPLG) antibody (FITC)SELPLG 适用: 人 FACS 宿主: 小鼠 Monoclonal TC2 FITC
anti-Selectin P Ligand (SELPLG) antibody (APC)SELPLG 适用: 人 FACS 宿主: 小鼠 Monoclonal TC2 APC
anti-Selectin P Ligand (SELPLG) (N-Term) antibodySELPLG 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Selectin P Ligand (SELPLG) antibodySELPLG 适用: 人 IHC, ELISA 宿主: 兔 Monoclonal 3G11 unconjugated Recombinant Antibody
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Fuhlbrigge, R. C., Kieffer, J. D., Armerding, D., Kupper, T. S. Cutaneous lymphocyte antigen is a specialized form of PSGL-1 expressed on skin-homing T cells. Nature 389: 978-981, 1997. 2. Herron, M. J., Nelson, C. M., Larson, J., Snapp, K. R., Kansas, G. S., Goodman, J. L. Intracellular parasitism by the human granulocytic ehrlichiosis bacterium through the P-selectin ligand, PSGL-1. Science 288: 1653-1656, 2000. 3. Hidalgo, A., Weiss, L. A., Frenette, P. S. Functional selectin ligands mediating human CD34+ cell interactions with bone marrow endothelium are enhanced postnatally. J. Clin. Invest. 110: 559-569, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SELPLG (Selectin P Ligand (SELPLG))
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别名
- Selplg
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背景
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Synonyms: P-selectin glycoprotein ligand 1, PSGL-1, Selectin P ligand, CD162, Selplg, Selp1, Selpl
Tissue Specificity: Highly expressed in blood, bone marrow, brain, adipose tissue, spleen, and thymus. Also expressed in heart, kidney, liver, muscle, ovary, and stomach.
Background: Selectin P ligand, also known as SELPLG or CD162 (cluster of differentiation 162), is a human gene. It is mapped to 5 F, 5 55.59 cM. This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.
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分子量
- 110-120 kDa
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基因ID
- 20345
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UniProt
- Q62170
抗原
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