MATK 抗体 (AA 18-298)
Quick Overview for MATK 抗体 (AA 18-298) (ABIN7600327)
抗原
See all MATK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 18-298
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原理
- Anti-MATK Antibody Picoband®
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产品特性
- Anti-MATK Antibody Picoband® (ABIN7600327). Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MATK recombinant protein (Position: S18-Q298). Human MATK shares 88.5% and 91.4% amino acid (aa) sequence identity with mouse and rat MATK, respectively.
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anti-Megakaryocyte-Associated tyrosine Kinase (MATK) (AA 393-507) antibody
MATK 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Megakaryocyte-Associated tyrosine Kinase (MATK) (Internal Region) antibodyMATK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Megakaryocyte-Associated tyrosine Kinase (MATK) (AA 352-466) antibodyMATK 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Megakaryocyte-Associated tyrosine Kinase (MATK) antibodyMATK 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 9D7 unconjugated
anti-Megakaryocyte-Associated tyrosine Kinase (MATK) antibodyMATK 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Megakaryocyte-Associated tyrosine Kinase (MATK) (AA 422-507) antibodyMATK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C5 unconjugated
anti-Megakaryocyte-Associated tyrosine Kinase (MATK) (AA 250-464) antibodyMATK 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Megakaryocyte-Associated tyrosine Kinase (MATK) (AA 1-173) antibodyMATK 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Megakaryocyte-Associated tyrosine Kinase (MATK) (N-Term) antibodyMATK 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Megakaryocyte-Associated tyrosine Kinase (MATK) antibodyMATK 适用: 人 WB, EIA 宿主: 小鼠 Monoclonal 9D7 unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Avraham, S., Jiang, S., Ota, S., Fu, Y., Deng, B., Dowler, L. L., White, R. A., Avraham, H. Structural and functional studies of the intracellular tyrosine kinase MATK gene and its translated product. J. Biol. Chem. 270: 1833-1842, 1995. 2. Bennett, B. D., Cowley, S., Jiang, S., London, R., Deng, B., Grabarek, J., Groopman, J. E., Goeddel, D. V., Avraham, H. Identification and characterization of a novel tyrosine kinase from megakaryocytes. J. Biol. Chem. 269: 1068-1074, 1994. 3. Klages, S., Adam, D., Class, K., Fargnoli, J., Bolen, J. B., Penhallow, R. C. Ctk: a protein-tyrosine kinase related to Csk that defines an enzyme family. Proc. Nat. Acad. Sci. 91: 2597-2601, 1994. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))
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别名
- MATK
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背景
- Megakaryocyte-associated tyrosine-protein kinase is an enzyme that in humans is encoded by the MATK gene. The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.
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分子量
- 52 kDa
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基因ID
- 4145
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UniProt
- P42679
抗原
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