TSC22D1 抗体 (AA 179-926)
Quick Overview for TSC22D1 抗体 (AA 179-926) (ABIN7600310)
抗原
See all TSC22D1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 179-926
-
原理
- Anti-TSC22D1 Antibody Picoband®
-
交叉反应 (详细)
- No cross-reactivity with other proteins.
-
产品特性
- Anti-TSC22D1 Antibody Picoband® (ABIN7600310). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human TSC22D1 recombinant protein (Position: N179-Q926).
-
亚型
- IgG
-
-
-
-
应用备注
-
Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Jay, P., Ji, J. W., Marsollier, C., Taviaux, S., Berge-Lefranc, J.-L., Berta, P. Cloning of the human homologue of the TGF-beta-stimulated clone 22 gene. Biochem. Biophys. Res. Commun. 222: 821-826, 1996. 2. Kester, H. A., Blanchetot, C., den Hertog, J., van der Saag, P. T., van der Burg, B. Transforming growth factor-beta-stimulated clone-22 is a member of a family of leucine zipper proteins that can homo- and heterodimerize and has transcriptional repressor activity. J. Biol. Chem. 274: 27439-27447, 1999. 3. Ohta, S., Shimekake, Y., Nagata, K. Molecular cloning and characterization of a transcription factor for the C-type natriuretic peptide gene promoter. Europ. J. Biochem. 242: 460-466, 1996. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- TSC22D1 (TSC22 Domain Family, Member 1 (TSC22D1))
-
别名
- TSC22D1
-
背景
-
Synonyms: Rho-related GTP-binding protein Rho6,Rho family GTPase 1,Rnd1,RND1,RHO6,
Tissue Specificity: Mostly expressed in brain and liver.
Background: TSC22 domain family protein 1 is a protein that in humans is encoded by the TSC22D1 gene. This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
-
分子量
- 140-150 kDa
-
基因ID
- 8848
-
UniProt
- Q15714
抗原
-