ADRB3 抗体 (AA 179-250)
Quick Overview for ADRB3 抗体 (AA 179-250) (ABIN7600307)
抗原
See all ADRB3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 179-250
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原理
- Anti-beta 3 Adrenergic Receptor/ADRB3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-beta 3 Adrenergic Receptor/ADRB3 Antibody Picoband® (ABIN7600307). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human beta 3 Adrenergic Receptor/ADRB3 recombinant protein (Position: R179-S250).
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亚型
- IgG
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anti-Adrenergic, beta-3-, Receptor (ADRB3) (AA 310-408) antibody
ADRB3 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-3-, Receptor (ADRB3) (AA 1-100) antibodyADRB3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-3-, Receptor (ADRB3) (N-Term) antibodyADRB3 适用: 人, 大鼠 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-3-, Receptor (ADRB3) (AA 1-408) antibodyADRB3 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Adrenergic, beta-3-, Receptor (ADRB3) (AA 180-192), (C186S), (Extracellular) antibodyADRB3 适用: 小鼠 WB, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-3-, Receptor (ADRB3) (Internal Region) antibodyRecent ADRB3 适用: 小鼠 ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Adrenergic, beta-3-, Receptor (ADRB3) (AA 1-36) antibodyADRB3 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-3-, Receptor (ADRB3) (AA 216-249) antibodyADRB3 适用: 人 WB 宿主: 兔 Polyclonal RB53477 unconjugated
anti-Adrenergic, beta-3-, Receptor (ADRB3) (AA 255-289) antibodyADRB3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB53334 unconjugated
anti-Adrenergic, beta-3-, Receptor (ADRB3) (N-Term) antibodyVerified ADRB3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bachman, E. S., Dhillon, H., Zhang, C.-Y., Cinti, S., Bianco, A. C., Kobilka, B. K., Lowell, B. B. Beta-AR signaling required for diet-induced thermogenesis and obesity resistance. Science 297: 843-845, 2002. 2. Buettner, R., Schaffler, A., Arndt, H., Rogler, G., Nusser, J., Zietz, B., Enger, I., Hugl, S., Cuk, A., Scholmerich, J., Palitzsch, K.-D. The trp64arg polymorphism of the beta-3-adrenergic receptor gene is not associated with obesity or type 2 diabetes mellitus in a large population-based Caucasian cohort. J. Clin. Endocr. Metab. 83: 2892-2897, 1998. 3. Cagliani, R., Fumagalli, M., Pozzoli, U., Riva, S., Comi, G. P., Torri, F., Macciardi, F., Bresolin, N., Sironi, M. Diverse evolutionary histories for beta-adrenoreceptor genes in humans. Am. J. Hum. Genet. 85: 64-75, 2009. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))
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别名
- ADRB3
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背景
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Synonyms: Beta-3 adrenergic receptor, Beta-3 adrenoreceptor, Beta-3 adrenoceptor, ADRB3, ADRB3R, B3AR
Tissue Specificity: Expressed mainly in adipose tissues.
Background: The beta-3 adrenergic receptor (β3 adrenoreceptor), also known as ADRB3, is a beta-adrenergic receptor, and also denotes the human gene encoding it. It is mapped to 8p11.23. The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Obesity and bodyweight-related disorders are correlated with certain polymorphisms in three subtypes of beta-adrenoceptor, among them, the ADRB3 gene.
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分子量
- 44 kDa
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基因ID
- 155
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UniProt
- P13945
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途径
- cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Brown Fat Cell Differentiation
抗原
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