Anti-PIPOX Antibody Picoband® (ABIN7600291). Tested in WB, IHC, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
纯化方法
Immunogen affinity purified.
免疫原
E.coli-derived human PIPOX recombinant protein (Position: E173-L390). Human PIPOX shares 81.2% amino acid (aa) sequence identity with mouse PIPOX.
Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry, 2-5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, - 1. Dodt, G., Kim, D., Reimann, S., McCabe, K., Gould, S. J., Mihalik, S. J. The human L-pipecolic acid oxidase is similar to bacterial monomeric sarcosine oxidases rather than D-amino acid oxidases. Cell Biochem. Biophys. 32: 313-316, 2000. 2. Dodt, G., Kim, D. G., Reimann, S. A., Reuber, B. E., McCabe, K., Gould, S. J., Mihalik, S. J. L-pipecolic acid oxidase, a human enzyme essential for the degradation of L-pipecolic acid, is most similar to the monomeric sarcosine oxidases. Biochem. J. 345: 487-494, 2000. 3. IJlst, L., de Kromme, I., Oostheim, W., Wanders, R. J. A. Molecular cloning and expression of human L-pipecolate oxidase. Biochem. Biophys. Res. Commun. 270: 1101-1105, 2000.
限制
仅限研究用
状态
Lyophilized
溶解方式
Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
抗原
PIPOX
(Pipecolic Acid Oxidase (PIPOX))
别名
PIPOX
背景
PIPOX (Pipecolic Acid And Sarcosine Oxidase, also known as L-pipecolate oxidase) is a Protein Coding gene. The PIPOX gene, located on 17q11.2, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, C.elegans, S.pombe, N.crassa, A.thaliana, rice, and frog. This enzyme oxidizes L-pipecolic acid with the concomitant production of H2O2 in the peroxisome of the normal human liver. Pipecolate, an intermediate of the lysine catabolic pathway, is oxidized to Δ1 -piperideine-6-carboxylate (P6C) by the PIPOX. Diseases associated with PIPOX include Inflammatory Bowel Disease 15 and Zellweger Syndrome. Among its related pathways are Lysine degradation and Viral mRNA Translation. 215 organisms have orthologs with the human gene PIPOX.