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PIPOX 抗体 (AA 173-390)

This anti-PIPOX antibody is a 兔 多克隆 antibody detecting PIPOX in ELISA, WB 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7600291
发货至: 中国

Quick Overview for PIPOX 抗体 (AA 173-390) (ABIN7600291)

抗原

See all PIPOX 抗体
PIPOX (Pipecolic Acid Oxidase (PIPOX))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This PIPOX antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 173-390

    原理

    Anti-PIPOX Antibody Picoband®

    产品特性

    Anti-PIPOX Antibody Picoband® (ABIN7600291). Tested in WB, IHC, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PIPOX recombinant protein (Position: E173-L390). Human PIPOX shares 81.2% amino acid (aa) sequence identity with mouse PIPOX.
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry, 2-5 μg/mL, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Dodt, G., Kim, D., Reimann, S., McCabe, K., Gould, S. J., Mihalik, S. J. The human L-pipecolic acid oxidase is similar to bacterial monomeric sarcosine oxidases rather than D-amino acid oxidases. Cell Biochem. Biophys. 32: 313-316, 2000. 2. Dodt, G., Kim, D. G., Reimann, S. A., Reuber, B. E., McCabe, K., Gould, S. J., Mihalik, S. J. L-pipecolic acid oxidase, a human enzyme essential for the degradation of L-pipecolic acid, is most similar to the monomeric sarcosine oxidases. Biochem. J. 345: 487-494, 2000. 3. IJlst, L., de Kromme, I., Oostheim, W., Wanders, R. J. A. Molecular cloning and expression of human L-pipecolate oxidase. Biochem. Biophys. Res. Commun. 270: 1101-1105, 2000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    PIPOX (Pipecolic Acid Oxidase (PIPOX))

    别名

    PIPOX

    背景

    PIPOX (Pipecolic Acid And Sarcosine Oxidase, also known as L-pipecolate oxidase) is a Protein Coding gene. The PIPOX gene, located on 17q11.2, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, C.elegans, S.pombe, N.crassa, A.thaliana, rice, and frog. This enzyme oxidizes L-pipecolic acid with the concomitant production of H2O2 in the peroxisome of the normal human liver. Pipecolate, an intermediate of the lysine catabolic pathway, is oxidized to Δ1 -piperideine-6-carboxylate (P6C) by the PIPOX. Diseases associated with PIPOX include Inflammatory Bowel Disease 15 and Zellweger Syndrome. Among its related pathways are Lysine degradation and Viral mRNA Translation. 215 organisms have orthologs with the human gene PIPOX.

    分子量

    40 kDa

    基因ID

    51268

    UniProt

    Q9P0Z9
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