NAF1 抗体 (AA 173-340)
Quick Overview for NAF1 抗体 (AA 173-340) (ABIN7600289)
抗原
See all NAF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 173-340
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原理
- Anti-NAF1 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-NAF1 Antibody Picoband® (ABIN7600289). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NAF1 recombinant protein (Position: K173-E340).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hartz, P. A. Personal Communication. Baltimore, Md. 2/7/2018. 2. Hoareau-Aveilla, C., Bonoli, M., Caizergues-Ferrer, M., Henry, Y. hNaf1 is required for accumulation of human box H/ACA snoRNPs, scaRNPs, and telomerase. RNA 12: 832-840, 2006. 3. Stanley, S. E., Gable, D. L., Wagner, C. L., Carlile, T. M., Hanumanthu, V. S., Podlevsky, J. D., Khalil, S. E., DeZern, A. E., Rojas-Duran, M. F., Applegate, C. D., Alder, J. K., Parry, E. M., Gilbert, W. V., Armanios, M. Loss-of-function mutations in the RNA biogenesis factor NAF1 predispose to pulmonary fibrosis-emphysema. Sci. Transl. Med. 8: 351ra107, 2016. Note: Electronic Article. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NAF1 (Nuclear ssembly factor 1 ribonucleoprotein (NAF1))
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别名
- NAF1
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背景
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Synonyms: Homeobox protein SIX3,Sine oculis homeobox homolog 3,SIX3,
Tissue Specificity: Highly expressed in placenta, lung, kidney, testis and ovary. Weakly expressed in spleen and thymus. Not expressed in peripheral blood lymphocytes. Detected in hippocampus.
Background: Enables identical protein binding activity and telomerase RNA binding activity. Involved in regulation of nucleobase-containing compound metabolic process, ribosome biogenesis, and telomerase holoenzyme complex assembly. Located in nucleoplasm. Part of sno(s)RNA-containing ribonucleoprotein complex.
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分子量
- 70 kDa
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基因ID
- 92345
抗原
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