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LNPEP 抗体 (AA 17-994)

This anti-LNPEP antibody is a 兔 多克隆 antibody detecting LNPEP in WB, IHC 和 ELISA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7600279
发货至: 中国

Quick Overview for LNPEP 抗体 (AA 17-994) (ABIN7600279)

抗原

See all LNPEP 抗体
LNPEP (Leucyl/cystinyl Aminopeptidase (LNPEP))

适用

人, 大鼠, 小鼠

宿主

  • 21
  • 4
  • 1

克隆类型

  • 24
  • 2
多克隆

标记

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  • 1
  • 1
  • 1
  • 1
This LNPEP antibody is un-conjugated

应用范围

  • 26
  • 13
  • 11
  • 10
  • 7
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 17-994

    原理

    Anti-LNPEP Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-LNPEP Antibody Picoband® (ABIN7600279). Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human LNPEP recombinant protein (Position: E17-T994).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Beckman, L., Beckman, G., Mi, M. P., De Simone, J. The human placental amino acid naphthylamidases: their molecular interrelations and correlations with perinatal factors. Hum. Hered. 19: 249-257, 1969. 2. Beckman, L., Bjorling, G., Christodoulou, C. Pregnancy enzymes and placental polymorphism. II. Leucine aminopeptidase. Acta Genet. Statist. Med. 16: 122-131, 1966. 3. Horio, J., Nomura, S., Okada, M., Katsumata, Y., Nakanishi, Y., Kumano, Y., Takami, S., Kinoshita, M., Tsujimoto, M., Nakazato, H., Mizutani, S. Structural organization of the 5-prime-end and chromosomal assignment of human placental leucine aminopeptidase/insulin-regulated membrane aminopeptidase gene. Biochem. Biophys. Res. Commun. 262: 269-274, 1999.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    LNPEP (Leucyl/cystinyl Aminopeptidase (LNPEP))

    别名

    LNPEP

    背景

    Synonyms: Sentrin-specific protease 6, SUMO-1-specific protease 1, Sentrin/SUMO-specific protease SENP6, SENP6, KIAA0797, SSP1, SUSP1, FKSG6

    Tissue Specificity: Expressed in many tissues, highest levels in skeletal muscle.

    Background: Leucyl/cystinyl aminopeptidase, also known as cystinyl aminopeptidase (CAP), insulin-regulated aminopeptidase (IRAP), human placental leucine aminopeptidase (PLAP), oxytocinase, and vasopressinase, is an enzyme of the aminopeptidase group that in humans is encoded by the LNPEP gene. This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms.

    分子量

    117 kDa

    基因ID

    4012

    途径

    Regulation of long-term Neuronal Synaptic Plasticity
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