GBA2 抗体 (AA 17-869)
Quick Overview for GBA2 抗体 (AA 17-869) (ABIN7600278)
抗原
See all GBA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 17-869
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原理
- Anti-GBA2 Antibody Picoband®
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产品特性
- Anti-GBA2 Antibody Picoband® (ABIN7600278). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GBA2 recombinant protein (Position: E17-Q869). Human GBA2 shares 88.5% and 90.2% amino acid (aa) sequence identity with mouse and rat GBA2, respectively.
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anti-Glucosidase, beta (Bile Acid) 2 (GBA2) (Internal Region) antibody
GBA2 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Glucosidase, beta (Bile Acid) 2 (GBA2) (AA 656-867) antibodyGBA2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glucosidase, beta (Bile Acid) 2 (GBA2) antibodyGBA2 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glucosidase, beta (Bile Acid) 2 (GBA2) (AA 593-623) antibodyGBA2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB55138 unconjugated
anti-Glucosidase, beta (Bile Acid) 2 (GBA2) (AA 1-927) antibodyGBA2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Glucosidase, beta (Bile Acid) 2 (GBA2) (AA 708-927) antibodyGBA2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Glucosidase, beta (Bile Acid) 2 (GBA2) (Center) antibodyGBA2 适用: 人 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Boot, R. G., Verhoek, M., Donker-Koopman, W., Strijland, A., van Marle, J., Overkleeft, H. S., Wennekes, T., Aerts, J. M. F. G. Identification of the non-lysosomal glucosylceramidase as beta-glucosidase 2. J. Biol. Chem. 282: 1305-1312, 2007. 2. Boukhris, A., Feki, I., Elleuch, N., Miladi, M. I., Boland-Auge, A., Truchetto, J., Mundwiller, E., Jezequel, N., Zelenika, D., Mhiri, C., Brice, A., Stevanin, G. A new locus (SPG46) maps to 9p21.2-q21.12 in a Tunisian family with a complicated autosomal recessive hereditary spastic paraplegia with mental impairment and thin corpus callosum. Neurogenetics 11: 441-448, 2010. 3. Hammer, M. B., Eleuch-Fayache, G., Schottlaender, L. V., Nehdi, H., Gibbs, J. R., Arepalli, S. K., Chong, S. B., Hernandez, D. G., Sailer, A., Liu, G., Mistry, P. K., Cai, H., Shrader, G., Sassi, C., Bouhlal, Y., Houlden, H., Hentati, F., Amouri, R., Singleton, A. B. Mutations in GBA2 cause autosomal-recessive cerebellar ataxia with spasticity. Am. J. Hum. Genet. 92: 245-251, 2013. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- GBA2 (Glucosidase, beta (Bile Acid) 2 (GBA2))
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别名
- GBA2
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背景
- GBA2 is the gene that encodes the enzyme non-lysosomal glucosylceramidase in humans. This gene encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides as endogenous compounds. Studies to determine subcellular localization of this protein in the liver indicated that the enzyme was mainly enriched in the microsomal fraction where it appeared to be confined to the endoplasmic reticulum. This putative transmembrane protein is thought to play a role in carbohydrate transport and metabolism.
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分子量
- 105 kDa
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基因ID
- 57704
抗原
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