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KIF11 抗体 (AA 17-716)

This anti-KIF11 antibody is a 兔 多克隆 antibody detecting KIF11 in WB, ELISA, IF, IHC, FACS 和 ICC. Suitable for 人.
产品编号 ABIN7600277
发货至: 中国

Quick Overview for KIF11 抗体 (AA 17-716) (ABIN7600277)

抗原

See all KIF11 抗体
KIF11 (Kinesin Family Member 11 (KIF11))

适用

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宿主

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克隆类型

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多克隆

标记

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This KIF11 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
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    AA 17-716

    原理

    Anti-Eg5/KIF11 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Eg5/KIF11 Antibody Picoband® (ABIN7600277). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Eg5/KIF11 recombinant protein (Position: K17-Q716).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x10^6 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Bartoli, K. M., Jakovljevic, J., Woolford, J. L., Jr., Saunders, W. S. Kinesin molecular motor Eg5 functions during polypeptide synthesis. Molec. Biol. Cell 22: 3420-3430, 2011. 2. Birtel, J., Gliem, M., Mangold, E., Tebbe, L., Spier, I., Muller, P. L., Holz, F. G., Neuhaus, C., Wolfrum, U., Bolz, H. J., Issa, P. C. Novel insights into the phenotypical spectrum of KIF11-associated retinopathy, including a new form of retinal ciliopathy. Invest. Ophthal. Vis. Sci. 58: 3950-3959, 2017. 3. Blangy, A., Lane, H. A., d'Herin, P., Harper, M., Kress, M., Nigg, E. A. Phosphorylation by p34(cdc2) regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo. Cell 83: 1159-1169, 1995.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    KIF11 (Kinesin Family Member 11 (KIF11))

    别名

    KIF11

    背景

    Synonyms: Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, Flavoprotein subunit of complex II, Fp, SDHA, SDH2, SDHF

    Tissue Specificity: Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon.

    Background: Kinesin-like protein KIF11 is a molecular motor protein that is essential in mitosis. In humans it is coded for by the gene KIF11. This gene encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis.

    分子量

    130 kDa

    基因ID

    3832

    UniProt

    P52732
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