HELLS 抗体 (AA 167-838)
Quick Overview for HELLS 抗体 (AA 167-838) (ABIN7600237)
抗原
See all HELLS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 167-838
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原理
- Anti-HELLS Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-HELLS Antibody Picoband® (ABIN7600237). Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HELLS recombinant protein (Position: N167-F838). Human HELLS shares 93% amino acid (aa) sequence identity with mouse HELLS.
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亚型
- IgG
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anti-Helicase, Lymphoid-Specific (HELLS) (AA 1-348) antibody
HELLS 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D10 unconjugated
anti-Helicase, Lymphoid-Specific (HELLS) (AA 550-600) antibodyHELLS 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Helicase, Lymphoid-Specific (HELLS) (AA 1-838) antibodyHELLS 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Helicase, Lymphoid-Specific (HELLS) (AA 1-838) antibodyHELLS 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Helicase, Lymphoid-Specific (HELLS) (AA 756-805) antibodyHELLS 适用: 人, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Helicase, Lymphoid-Specific (HELLS) (Middle Region) antibodyHELLS 适用: 人, 小鼠, 大鼠, 兔, 犬, 马, Cow, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. de Greef, J. C., Wang, J., Balog, J., den Dunnen, J. T., Frants, R. R., Straasheijm, K. R., Aytekin, C., van der Burg, M., Duprez, L., Ferster, A., Gennery, A. R., Gimelli, G., and 13 others. Mutations in ZBTB24 are associated with immunodeficiency, centromeric instability, and facial anomalies syndrome type 2. Am. J. Hum. Genet. 88: 796-804, 2011. 2. De La Fuente, R., Baumann, C., Fan, T., Schmidtmann, A., Dobrinski, I., Muegge, K. Lsh is required for meiotic chromosome synapsis and retrotransposon silencing in female germ cells. Nature Cell Biol. 8: 1448-1454, 2006. 3. Dennis, K., Fan, T., Geiman, T., Yan, Q., Muegge, K. Lsh, a member of the SNF2 family, is required for genome-wide methylation. Genes Dev. 15: 2940-2944, 2001. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- HELLS (Helicase, Lymphoid-Specific (HELLS))
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别名
- HELLS
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: Lymphoid-specific helicase (Lsh) is a member of the SNF2 helicase family of chromatin remodeling proteins that in humans is encoded by the HELLS gene. This gene encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Alternatively spliced transcript variants encoding different isoforms have been identified.
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分子量
- 97 kDa
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基因ID
- 3070
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途径
- Chromatin Binding
抗原
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