TLN1 抗体 (AA 1658-1876)
Quick Overview for TLN1 抗体 (AA 1658-1876) (ABIN7600228)
抗原
See all TLN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1658-1876
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原理
- Anti-Talin 1/TLN1 Antibody Picoband® (monoclonal, 2G10D2)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Talin 1/TLN1 Antibody Picoband® (monoclonal, 2G10D2) (ABIN7600228). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Talin 1/TLN1 recombinant protein (Position: Q1658-N1876).
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亚型
- IgG1
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anti-Talin 1 (TLN1) (AA 1052-1149) antibody
TLN1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1A11 unconjugated
anti-Talin 1 (TLN1) (AA 975-1181) antibodyTLN1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Talin 1 (TLN1) (AA 1-220) antibodyTLN1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Talin 1 (TLN1) (AA 1601-1750) antibody (FITC)TLN1 适用: 小鼠, 大鼠 IF (cc), IF (p) 宿主: 兔 Polyclonal FITC
anti-Talin 1 (TLN1) (AA 1052-1150) antibodyTLN1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1A11 unconjugated
anti-Talin 1 (TLN1) (AA 1324-1424) antibodyTLN1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C8 unconjugated
anti-Talin 1 (TLN1) (AA 1324-1424) antibodyTLN1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4G4 unconjugated
anti-Talin 1 (TLN1) (AA 1601-1750) antibodyTLN1 适用: 小鼠, 大鼠 ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Talin 1 (TLN1) (AA 2293-2536) antibodyTLN1 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Talin 1 (TLN1) (AA 92-399) antibodyTLN1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Rees, D. J. G., Ades, S. E., Singer, S. J., Hynes, R. O. : Sequence and domain structure of talin. Nature 347: 685-689, 1990. 2. Gilmore, A. P., Ohanian, V., Spurr, N. K., Critchley, D. R. : Localisation of the human gene encoding the cytoskeletal protein talin to chromosome 9p. Hum. Genet. 96: 221-224, 1995. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- TLN1 (Talin 1 (TLN1))
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别名
- TLN1
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背景
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Synonyms: "chromosomal protein, Nonhistone, HMG4 antibody|High mobility group (nonhistone chromosomal) protein 4 antibody|High mobility group box 3 antibody|High mobility group protein 2a antibody|High mobility group protein 4 antibody|High mobility group protein B3 antibody| High mobility group protein HMG4 antibody|HMG 4 antibody|HMG-2a antibody|HMG-4 antibody|HMG2A antibody|HMGB 3 antibody|HMGB3 antibody| HMGB3_HUMAN antibody|MGC90319 antibody|Non histone chromosomal protein antibody|Nonhistone chromosomal protein HMG4 antibody"
Tissue Specificity: Expressed predominantly in placenta.
Background: Talin-1 is a protein that in humans is encoded by the TLN1 gene. This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.
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分子量
- 250-270 kDa
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基因ID
- 7094
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UniProt
- Q9Y490
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途径
- Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location
抗原
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