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TLN1 抗体 (AA 1658-1876)

This anti-TLN1 antibody is a 兔 多克隆 antibody detecting TLN1 in WB, ELISA, IHC, ICC, IF 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7600227
发货至: 中国

Quick Overview for TLN1 抗体 (AA 1658-1876) (ABIN7600227)

抗原

See all TLN1 抗体
TLN1 (Talin 1 (TLN1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This TLN1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)
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    AA 1658-1876

    原理

    Anti-Talin 1/TLN1 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Talin 1/TLN1 Antibody Picoband® (ABIN7600227). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Talin 1/TLN1 recombinant protein (Position: Q1658-N1876).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Rees, D. J. G., Ades, S. E., Singer, S. J., Hynes, R. O. : Sequence and domain structure of talin. Nature 347: 685-689, 1990. 2. Gilmore, A. P., Ohanian, V., Spurr, N. K., Critchley, D. R. : Localisation of the human gene encoding the cytoskeletal protein talin to chromosome 9p. Hum. Genet. 96: 221-224, 1995.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    TLN1 (Talin 1 (TLN1))

    别名

    TLN1

    背景

    Synonyms: Talin-1, TLN1, KIAA1027, TLN

    Tissue Specificity: Placenta and skin. Predominantly expressed in mammary gland tissue.

    Background: Talin-1 is a protein that in humans is encoded by the TLN1 gene. This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.

    分子量

    270 kDa

    基因ID

    7094

    UniProt

    Q9Y490

    途径

    Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location
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