TLN1 抗体 (AA 1658-1876)
Quick Overview for TLN1 抗体 (AA 1658-1876) (ABIN7600227)
抗原
See all TLN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1658-1876
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原理
- Anti-Talin 1/TLN1 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Talin 1/TLN1 Antibody Picoband® (ABIN7600227). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Talin 1/TLN1 recombinant protein (Position: Q1658-N1876).
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Rees, D. J. G., Ades, S. E., Singer, S. J., Hynes, R. O. : Sequence and domain structure of talin. Nature 347: 685-689, 1990. 2. Gilmore, A. P., Ohanian, V., Spurr, N. K., Critchley, D. R. : Localisation of the human gene encoding the cytoskeletal protein talin to chromosome 9p. Hum. Genet. 96: 221-224, 1995. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- TLN1 (Talin 1 (TLN1))
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别名
- TLN1
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背景
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Synonyms: Talin-1, TLN1, KIAA1027, TLN
Tissue Specificity: Placenta and skin. Predominantly expressed in mammary gland tissue.
Background: Talin-1 is a protein that in humans is encoded by the TLN1 gene. This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.
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分子量
- 270 kDa
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基因ID
- 7094
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UniProt
- Q9Y490
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途径
- Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location
抗原
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