PUS7L 抗体 (AA 165-699)
Quick Overview for PUS7L 抗体 (AA 165-699) (ABIN7600226)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 165-699
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原理
- Anti-PUS7L Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-PUS7L Antibody Picoband® (ABIN7600226). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PUS7L recombinant protein (Position: R165-H699).
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亚型
- IgG
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anti-Pseudouridylate Synthase 7 Homolog-Like (PUS7L) (AA 1-701) antibody
PUS7L 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Pseudouridylate Synthase 7 Homolog-Like (PUS7L) (AA 1-300) antibodyPUS7L 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Pseudouridylate Synthase 7 Homolog-Like (PUS7L) (N-Term) antibodyPUS7L 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Jamieson, C.R., van der Burgt, I., Brady, A.F., van Reen, M., Elsawi, M.M., Hol, F., Jeffery, S., Patton, M.A. and Mariman, E. 1994. Mapping a gene for Noonan syndrome to the long arm of chromosome 12. Nat. Genet. 8: 357-360. 2. Yang, W. and Cole, W.G. 1998. Low basal transcripts of the COL2A1 collagen gene from lymphoblasts show alternative splicing of exon 12 in the Kniest form of spondyloepiphyseal dysplasia. Hum. Mutat. Suppl1: S1-S2. 3. Trowsdale, J., Barten, R., Haude, A., Stewart, C.A., Beck, S. and Wilson, M.J. 2001. The genomic context of natural killer receptor extended gene families. Immunol. Rev. 181: 20-38 -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PUS7L (Pseudouridylate Synthase 7 Homolog-Like (PUS7L))
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别名
- PUS7L
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背景
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Synonyms: RNA-binding protein 47,RNA-binding motif protein 47,RBM47,
Tissue Specificity: Abundantly expressed in tonsil, lymph node, and trachea, strong expression in prostate, lower expression in thyroid, stomach, and colon. .
Background: Pseudouridylate synthase 7 homolog-like protein is an enzyme that in humans is encoded by the PUS7L gene. PUS7L (pseudouridylate synthase 7 homolog (S. cerevisiae) -like) is a 701 amino acid protein that belongs to the pseudouridine synthase truD family and contains one TRUD domain. The PUS7L gene is conserved in chimpanzee, canine, bovine, mouse, chicken and zebrafish, and maps to human chromosome 12q12. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction.
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分子量
- 85 kDa
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基因ID
- 83448
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UniProt
- Q9H0K6
抗原
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