Osteoactivin 抗体 (AA 164-564)
Quick Overview for Osteoactivin 抗体 (AA 164-564) (ABIN7600217)
抗原
See all Osteoactivin (GPNMB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 164-564
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原理
- Anti-GPNMB/Gpnmb Picoband® Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-GPNMB/Gpnmb Picoband® Antibody (ABIN7600217). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse GPNMB/Gpnmb recombinant protein (Position: R164-D564).
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亚型
- IgG
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anti-Osteoactivin (GPNMB) (AA 81-180) antibody
GPNMB 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Osteoactivin (GPNMB) (AA 31-260) antibodyGPNMB 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 7C10E5 unconjugated
anti-Osteoactivin (GPNMB) (AA 104-203) antibodyGPNMB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A8 unconjugated
anti-Osteoactivin (GPNMB) (N-Term) antibodyGPNMB 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 犬, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Osteoactivin (GPNMB) (AA 104-203) antibodyGPNMB 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Osteoactivin (GPNMB) (AA 50-99) antibodyGPNMB 适用: 人, 小鼠, Cow, 马, 兔, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Osteoactivin (GPNMB) (AA 1-572) antibodyGPNMB 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3A5 unconjugated
anti-Osteoactivin (GPNMB) (AA 1-572) antibodyGPNMB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A5 unconjugated
anti-Osteoactivin (GPNMB) (AA 74-123) antibodyGPNMB 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 犬, 兔, 斑马鱼, Hamster, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Osteoactivin (GPNMB) (AA 22-260) antibodyGPNMB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Lu, H., Wang, X., Pullen, M., Guan, H., Chen, H., Sahu, S., Zhang, B., Chen, H., Williams, R. W., Geisert, E. E., Lu, L., Jablonski, M. M. Genetic dissection of the Gpnmb network in the eye. Invest. Ophthal. Vis. Sci. 52: 4132-4142, 2011. 2. Weterman, M. A. J., Ajubi, N., van Dinter, I. M. R., Degen, W. G. J., van Muijen, G. N. P., Ruiter, D. J., Bloemers, H. P. J. Nmb, a novel gene, is expressed in low-metastatic human melanoma cell lines and xenografts. Int. J. Cancer 60: 73-81, 1995. 3. Yang, C.-F., Lin, S.-P., Chiang, C.-P., Wu, Y.-H., H'ng, W. S., Chang, C.-P., Chen, Y.-T., Wu, J.-Y. Loss of GPNMB causes autosomal-recessive amyloidosis cutis dyschromica in humans. Am. J. Hum. Genet. 102: 219-232, 2018. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Osteoactivin (GPNMB)
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别名
- Gpnmb
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背景
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Synonyms: Transmembrane glycoprotein NMB, DC-HIL, Dendritic cell-associated transmembrane protein, Osteoactivin, Gpnmb, Dchil, Hgfin,Nmb
Tissue Specificity: Monocyte/macrophage specific.
Background: Transmembrane glycoprotein NMB is a protein that in humans is encoded by the GPNMB gene. It is mapped to 6 B2.3, 6 23.82 cM. The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
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分子量
- 64 kDa
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基因ID
- 93695
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UniProt
- Q99P91
抗原
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