IRF4 抗体 (AA 163-419)
Quick Overview for IRF4 抗体 (AA 163-419) (ABIN7600211)
抗原
See all IRF4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 163-419
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原理
- Anti-MUM1/IRF4 Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-MUM1/IRF4 Antibody Picoband® (ABIN7600211). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MUM1/IRF4 recombinant protein (Position: A163-Q419). Human IRF4 shares 93.4% amino acid (aa) sequence identity with mouse IRF4.
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亚型
- IgG
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anti-Interferon Regulatory Factor 4 (IRF4) (AA 342-451) antibody
IRF4 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 2D1 unconjugated
anti-Interferon Regulatory Factor 4 (IRF4) (AA 342-451) antibodyIRF4 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F2 unconjugated
anti-Interferon Regulatory Factor 4 (IRF4) (AA 342-452) antibodyIRF4 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2F2 unconjugated
anti-Interferon Regulatory Factor 4 (IRF4) (AA 393-407) antibodyVerified IRF4 适用: 人, 大鼠 WB, ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Interferon Regulatory Factor 4 (IRF4) (C-Term) antibodyIRF4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 4 (IRF4) (N-Term) antibodyIRF4 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 4 (IRF4) (AA 342-452) antibodyIRF4 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 2F2 unconjugated
anti-Interferon Regulatory Factor 4 (IRF4) (AA 175-433) antibodyIRF4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 4 (IRF4) (AA 180-451) antibodyIRF4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 4 (IRF4) (C-Term) antibodyVerified IRF4 适用: 人, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Shaffer, A. L., Emre, N. C. T., Lamy, L., Ngo, V. N., Wright, G., Xiao, W., Powell, J., Dave, S., Yu, X., Zhao, H., Zeng, Y., Chen, B., Epstein, J., Staudt, L. M. IRF4 addiction in multiple myeloma. Nature 454: 226-231, 2008. 2. Grossman A, Mittrucker HW, Nicholl J, Suzuki A, Chung S, Antonio L, Suggs S, Sutherland GR, Siderovski DP, Mak TW (Feb 1997). "Cloning of human lymphocyte-specific interferon regulatory factor (hLSIRF/hIRF4) and mapping of the gene to 6p23-p25". Genomics 37 (2): 229-33. 3. Hoek KS, Schlegel NC, Eichhoff OM, et al. (2008). "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell Melanoma Res. 21 (6): 665-76. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- IRF4 (Interferon Regulatory Factor 4 (IRF4))
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别名
- IRF4
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: Interferon regulatory factor 4 (IRF4), also known as MUM1, is a protein that in humans is encoded by the IRF4 gene. It is located on 6p25.3. IRF4 is a transcription factor, and it is essential for the development of T helper-2 (Th2) cells, IL17 -producing Th17 cells, and IL9 -producing Th9 cells. In melanocytic cells, the IRF4 gene may be regulated by MITF. IRF4 is a transcription factor that has been implicated in acute leukemia. This gene is strongly associated with pigmentation, sensitivity of skin to sun exposure, freckles, blue eyes, and brown hair color. What's more, IRF4 inhibition is toxic to myeloma cell lines, regardless of transforming oncogenic mechanism.
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分子量
- 60 kDa
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基因ID
- 3662
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UniProt
- Q15306
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途径
- Chromatin Binding
抗原
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