SWAP70 抗体 (AA 161-292)
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北京 101111
Quick Overview for SWAP70 抗体 (AA 161-292) (ABIN7600201)
抗原
See all SWAP70 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 161-292
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原理
- Anti-SWAP70 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SWAP70 Antibody (ABIN7600201). Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SWAP70 recombinant protein (Position: H161-K292).
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亚型
- IgG
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anti-SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) (AA 378-451) antibody
SWAP70 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H8 unconjugated
anti-SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) (AA 378-451) antibodySWAP70 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3H8 unconjugated
anti-SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) (AA 316-585) antibodySWAP70 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) (C-Term) antibodyVerified SWAP70 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) (AA 1-585) antibodySWAP70 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) (AA 1-585) antibodySWAP70 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) antibodySWAP70 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) antibodySWAP70 适用: 人, 小鼠 WB, IP 宿主: 小鼠 Monoclonal unconjugated
anti-SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) (AA 1-50) antibodySWAP70 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) antibodyKD Validated SWAP70 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB4225 unconjugated
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应用备注
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Western blot, 0.5-1 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))
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别名
- SWAP70
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背景
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Synonyms: Aflatoxin B1 aldehyde reductase member 2, AFB1 aldehyde reductase 1, AFB1-AR 1, Aldoketoreductase 7, Succinic semialdehyde reductase, SSA reductase, AKR7A2, AFAR, AFAR1, AKR7
Tissue Specificity: Expressed in basement membranes of lung and kidney. Muscle- and neuron-specific isoforms are found. Isoforms (y+) with the 4 AA insert and (z+8) isoforms with the 8 AA insert are all neuron-specific. Isoforms (z+11) are found in both neuronal and non-neuronal tissues.
Background: SWAP70 (Switch-associated protein 70) is a 67-70 kDa intracellular protein that bears limited resemblance to members of the Dbl-family of GEFs for small Rho GTPases. It is expressed in mast cells, dendritic cells and B cells. In mast cells, it promotes the release of anaphylactic mediators, in dendritic cells, it regulates the appearance of MHC II, and in B cells, it forms a nuclear complex that initiates immunoglobulin class switching. Human SWAP70 is 585 amino acids (aa) in length. It contains one plextrin homology (PH) domain (aa 213-304) plus a coiled-coil region (aa 316-539). There are three potential splice variants. One contains an alternative start site at Met70, another shows a deletion of aa 81-138, and a third possesses a 38 aa substitution for aa 453-585. Over aa 386-585, human SWAP70 shares 96 % aa identity with mouse SWAP70.
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分子量
- 69 kDa
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基因ID
- 23075
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途径
- Production of Molecular Mediator of Immune Response
抗原
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