TRIT1 抗体 (AA 16-415)
Quick Overview for TRIT1 抗体 (AA 16-415) (ABIN7600178)
抗原
See all TRIT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 16-415
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原理
- Anti-IPT/TRIT1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-IPT/TRIT1 Antibody Picoband® (ABIN7600178). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human IPT/TRIT1 recombinant protein (Position: L16-K415).
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亚型
- IgG
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anti-tRNA Isopentenyltransferase 1 (TRIT1) (AA 1-467) antibody
TRIT1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-tRNA Isopentenyltransferase 1 (TRIT1) (AA 121-220) antibodyTRIT1 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-tRNA Isopentenyltransferase 1 (TRIT1) (AA 1-324) antibodyTRIT1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-tRNA Isopentenyltransferase 1 (TRIT1) (AA 20-69) antibodyTRIT1 适用: 人, 小鼠, 马, 兔, 大鼠, 豚鼠, Cow, 犬, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-tRNA Isopentenyltransferase 1 (TRIT1) (AA 179-228) antibodyTRIT1 适用: 人, 马, 兔, 大鼠, Cow, 犬, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-tRNA Isopentenyltransferase 1 (TRIT1) (C-Term) antibodyTRIT1 适用: 人, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-tRNA Isopentenyltransferase 1 (TRIT1) (Middle Region) antibodyTRIT1 适用: 人, 小鼠, 大鼠, Cow, 犬, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-tRNA Isopentenyltransferase 1 (TRIT1) (C-Term) antibodyTRIT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Golovko, A., Hjalm, G., Sitbon, F., Nicander, B. Cloning of a human tRNA isopentenyl transferase. Gene 258: 85-93, 2000. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 1/19/2018. 3. Kernohan, K. D., Dyment, D. A., Pupavac, M., Cramer, Z., McBride, A., Bernard, G., Straub, I., Tetreault, M., Hartley, T., Huang, L., Sell, E., Majewski, J., and 14 others. Matchmaking facilitates the diagnosis of an autosomal-recessive mitochondrial disease caused by biallelic mutation of the tRNA isopentenyltransferase (TRIT1) gene. Hum. Mutat. 38: 511-516, 2017. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- TRIT1 (tRNA Isopentenyltransferase 1 (TRIT1))
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别名
- TRIT1
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背景
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Synonyms: Mediator of RNA polymerase II transcription subunit 8, Activator-recruited cofactor 32 kDa component, ARC32, Mediator complex subunit 8, MED8,
Tissue Specificity: Ubiquitous.
Background: tRNA isopentenyltransferase, mitochondrial is an enzyme that in humans is encoded by the TRIT1 gene. This gene encodes a protein that that is targeted to the mitochondrion and modifies transfer RNAs (tRNAs) by adding a dimethylallyl group onto the adenine at position 37. This modification is important for maintaining the correct reading frame during protein translation. This gene is considered a tumor suppressor and its expression can decrease cell growth. Alternative splicing results in multiple transcripts variants, most of which are likely non-functional.
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分子量
- 53 kDa
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基因ID
- 54802
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UniProt
- Q9H3H1
抗原
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