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HSD17B7 抗体 (AA 16-336)

This anti-HSD17B7 antibody is a 兔 多克隆 antibody detecting HSD17B7 in WB, ELISA, IHC, FACS, IF 和 ICC. Suitable for 人 和 大鼠.
产品编号 ABIN7600174
发货至: 中国

Quick Overview for HSD17B7 抗体 (AA 16-336) (ABIN7600174)

抗原

See all HSD17B7 抗体
HSD17B7 (Hydroxysteroid (17-Beta) Dehydrogenase 7 (HSD17B7))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This HSD17B7 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)
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    AA 16-336

    原理

    Anti-HSD17B7 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-HSD17B7 Antibody Picoband® (ABIN7600174). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human HSD17B7 recombinant protein (Position: L16-L336).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Jokela, H., Rantakari, P., Lamminen, T., Strauss, L., Ola, R., Mutka, A.-L., Gylling, H., Miettinen, T., Pakarinen, P., Sainio, K., Poutanen, M. Hydroxysteroid (17-beta) dehydrogenase 7 activity is essential for fetal de novo cholesterol synthesis and for neuroectodermal survival and cardiovascular differentiation in early mouse embryos. Endocrinology 151: 1884-1892, 2010. 2. Krazeisen, A., Breitling, R., Imai, K., Fritz, S., Moller, G., Adamski, J. Determination of cDNA, gene structure and chromosomal localization of the novel human 17-beta-hydroxysteroid dehydrogenase type 7. FEBS Lett. 460: 373-379, 1999. 3. Marijanovic, Z., Laubner, D., Moller, G., Gege, C., Husen, B., Adamski, J., Breitling, R. Closing the gap: identification of human 3-ketosteroid reductase, the last unknown enzyme of mammalian cholesterol biosynthesis. Molec. Endocr. 17: 1715-1725, 2003.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    HSD17B7 (Hydroxysteroid (17-Beta) Dehydrogenase 7 (HSD17B7))

    别名

    HSD17B7

    背景

    Synonyms: T-lymphocyte surface antigen Ly-9, Cell surface molecule Ly-9, Lymphocyte antigen 9, SLAM family member 3, SLAMF3, Signaling lymphocytic activation molecule 3, CD229, LY9, CDABP0070

    Tissue Specificity: Increased surface expression on T-cells of systemic lupus erythematosus (SLE) patients.

    Background: 3-keto-steroid reductase is an enzyme that in humans is encoded by the HSD17B7 gene. HSD17B7 encodes an enzyme that functions both as a 17-beta-hydroxysteroid dehydrogenase (EC 1.1.1.62) in the biosynthesis of sex steroids and as a 3-ketosteroid reductase (EC 1.1.1.270) in the biosynthesis of cholesterol.

    分子量

    38 kDa

    基因ID

    51478

    UniProt

    P56937

    途径

    Steroid Hormone Biosynthesis
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