HSD17B7 抗体 (AA 16-336)
Quick Overview for HSD17B7 抗体 (AA 16-336) (ABIN7600174)
抗原
See all HSD17B7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 16-336
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原理
- Anti-HSD17B7 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-HSD17B7 Antibody Picoband® (ABIN7600174). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HSD17B7 recombinant protein (Position: L16-L336).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Jokela, H., Rantakari, P., Lamminen, T., Strauss, L., Ola, R., Mutka, A.-L., Gylling, H., Miettinen, T., Pakarinen, P., Sainio, K., Poutanen, M. Hydroxysteroid (17-beta) dehydrogenase 7 activity is essential for fetal de novo cholesterol synthesis and for neuroectodermal survival and cardiovascular differentiation in early mouse embryos. Endocrinology 151: 1884-1892, 2010. 2. Krazeisen, A., Breitling, R., Imai, K., Fritz, S., Moller, G., Adamski, J. Determination of cDNA, gene structure and chromosomal localization of the novel human 17-beta-hydroxysteroid dehydrogenase type 7. FEBS Lett. 460: 373-379, 1999. 3. Marijanovic, Z., Laubner, D., Moller, G., Gege, C., Husen, B., Adamski, J., Breitling, R. Closing the gap: identification of human 3-ketosteroid reductase, the last unknown enzyme of mammalian cholesterol biosynthesis. Molec. Endocr. 17: 1715-1725, 2003. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- HSD17B7 (Hydroxysteroid (17-Beta) Dehydrogenase 7 (HSD17B7))
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别名
- HSD17B7
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背景
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Synonyms: T-lymphocyte surface antigen Ly-9, Cell surface molecule Ly-9, Lymphocyte antigen 9, SLAM family member 3, SLAMF3, Signaling lymphocytic activation molecule 3, CD229, LY9, CDABP0070
Tissue Specificity: Increased surface expression on T-cells of systemic lupus erythematosus (SLE) patients.
Background: 3-keto-steroid reductase is an enzyme that in humans is encoded by the HSD17B7 gene. HSD17B7 encodes an enzyme that functions both as a 17-beta-hydroxysteroid dehydrogenase (EC 1.1.1.62) in the biosynthesis of sex steroids and as a 3-ketosteroid reductase (EC 1.1.1.270) in the biosynthesis of cholesterol.
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分子量
- 38 kDa
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基因ID
- 51478
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UniProt
- P56937
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途径
- Steroid Hormone Biosynthesis
抗原
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