NDFIP2 抗体 (AA 16-336)
Quick Overview for NDFIP2 抗体 (AA 16-336) (ABIN7600173)
抗原
See all NDFIP2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 16-336
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原理
- Anti-NDFIP2 Antibody Picoband® (monoclonal, 10D6D7)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-NDFIP2 Antibody Picoband® (monoclonal, 10D6D7) (ABIN7600173). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NDFIP2 recombinant protein (Position: M16-L336).
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亚型
- IgG2b
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anti-Nedd4 Family Interacting Protein 2 (NDFIP2) (AA 1-242) antibody
NDFIP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C7 unconjugated
anti-Nedd4 Family Interacting Protein 2 (NDFIP2) (Internal Region) antibodyNDFIP2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nedd4 Family Interacting Protein 2 (NDFIP2) (AA 152-201) antibodyNDFIP2 适用: 人, 小鼠, Cow, 犬, 马, 大鼠, 斑马鱼, 豚鼠, Pig, Bat, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Nedd4 Family Interacting Protein 2 (NDFIP2) (AA 1-242) antibodyNDFIP2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Nedd4 Family Interacting Protein 2 (NDFIP2) (AA 251-300) antibodyNDFIP2 适用: 人, 小鼠, Cow, 犬, 马, 大鼠, 斑马鱼, Pig, 兔, Bat, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Nedd4 Family Interacting Protein 2 (NDFIP2) (Middle Region) antibodyNDFIP2 适用: 人, 小鼠, Cow, 犬, 马, 大鼠, 斑马鱼, 豚鼠, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Nedd4 Family Interacting Protein 2 (NDFIP2) (N-Term) antibodyNDFIP2 适用: 人, 小鼠, Cow, 犬, 马, 大鼠, 斑马鱼, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Cristillo, A. D., Nie, L., Macri, M. J., Bierer, B. E. Cloning and characterization of N4WBP5A, an inducible, cyclosporine-sensitive, Nedd4-binding protein in human T lymphocytes. J. Biol. Chem. 278: 34587-34597, 2003. 2. Hirosawa, M., Nagase, T., Ishikawa, K., Kikuno, R., Nomura, N., Ohara, O. Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. DNA Res. 6: 329-336, 1999. 3. Konstas, A.-A., Shearwin-Whyatt, L. M., Fotia, A. B., Degger, B., Riccardi, D., Cook, D. I., Korbmacher, C., Kumar, S. Regulation of the epithelial sodium channel by N4WBP5A, a novel Nedd4/Nedd4-2-interacting protein. J. Biol. Chem. 277: 29406-29416, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))
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别名
- NDFIP2
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背景
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Synonyms: T-complex protein 1 subunit gamma, TCP-1-gamma, CCT-gamma, hTRiC5, CCT3, CCTG, TRIC5
Tissue Specificity: Ubiquitously expressed with highest levels in spleen, thymus and immature brain.
Background: NEDD4 family-interacting protein 2 is a protein that in humans is encoded by the NDFIP2 gene. The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.
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分子量
- 39 kDa
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基因ID
- 54602
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途径
- Negative Regulation of Transporter Activity, SARS-CoV-2 Protein Interactome
抗原
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