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ZIC1 抗体 (AA 16-195)

This anti-ZIC1 antibody is a 兔 多克隆 antibody detecting ZIC1 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7600166
发货至: 中国

Quick Overview for ZIC1 抗体 (AA 16-195) (ABIN7600166)

抗原

See all ZIC1 抗体
ZIC1 (Zinc Finger Protein ZIC 1 (ZIC1))

适用

  • 49
  • 35
  • 25
  • 3
  • 2
  • 2
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  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 47
  • 8
  • 1

克隆类型

  • 39
  • 17
多克隆

标记

  • 26
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This ZIC1 antibody is un-conjugated

应用范围

  • 42
  • 16
  • 13
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  • 7
  • 6
  • 4
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  • 3
  • 3
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  • 1
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Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 16-195

    原理

    Anti-ZIC1 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-ZIC1 Antibody Picoband® (ABIN7600166). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human ZIC1 recombinant protein (Position: T16-H195).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Aruga, J., Yokota, N., Hashimoto, M., Furuichi, T., Fukuda, M., Mikoshiba, K. A novel zinc finger protein, Zic, is involved in neurogenesis, especially in the cell lineage of cerebellar granule cells. J. Neurochem. 63: 1880-1890, 1994. 2. Grinberg, I., Northrup, H., Ardinger, H., Prasad, C., Dobyns, W. B., Millen, K. J. Heterozygous deletion of the linked genes ZIC1 and ZIC4 is involved in Dandy-Walker malformation. Nature Genet. 36: 1053-1055, 2004. 3. Salero, E., Perez-Sen, R., Aruga, J., Gimenez, C., Zafra, F. Transcription factors Zic1 and Zic2 bind and transactivate the apolipoprotein E gene promoter. J. Biol. Chem. 276: 1881-1888, 2001.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    ZIC1 (Zinc Finger Protein ZIC 1 (ZIC1))

    别名

    ZIC1

    背景

    Synonyms: Spermine oxidase, Polyamine oxidase 1, PAO-1, PAOh1, Smox, Smo

    Tissue Specificity: Widely expressed. Isoform 1 and isoform 2 are expressed at higher level in brain and skeletal muscle. Isoform 7 is found in brain and spleen, isoform 10 is widely expressed but found at lower level in heart, kidney, liver and lung.

    Background: ZIC1 is a member of the Zinc finger of the cerebellum (ZIC) protein family. This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene.

    分子量

    48 kDa

    基因ID

    7545

    UniProt

    Q15915
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