CPN1 抗体 (AA 158-208)
Quick Overview for CPN1 抗体 (AA 158-208) (ABIN7600158)
抗原
See all CPN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 158-208
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原理
- Anti-CPN1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-CPN1 Antibody Picoband® (ABIN7600158). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CPN1 recombinant protein (Position: D158-N208).
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亚型
- IgG
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anti-Carboxypeptidase N Subunit 1 (CPN1) (AA 159-325) antibody
CPN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase N Subunit 1 (CPN1) (AA 209-458) antibodyCPN1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase N Subunit 1 (CPN1) (AA 251-300) antibodyCPN1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase N Subunit 1 (CPN1) (C-Term) antibodyCPN1 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase N Subunit 1 (CPN1) (AA 52-81), (N-Term) antibodyCPN1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB19020 unconjugated
anti-Carboxypeptidase N Subunit 1 (CPN1) (AA 210-240) antibodyCPN1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19021 unconjugated
anti-Carboxypeptidase N Subunit 1 (CPN1) (AA 221-449) antibodyCPN1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase N Subunit 1 (CPN1) (C-Term) antibodyCPN1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase N Subunit 1 (CPN1) (AA 209-458) antibodyCPN1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase N Subunit 1 (CPN1) (AA 323-372) antibodyCPN1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Cao, H., Hegele, R. A. DNA polymorphism and mutations in CPN1, including the genomic basis of carboxypeptidase N deficiency. J. Hum. Genet. 48: 20-22, 2003. 2. Gebhard, W., Schube, M., Eulitz, M. cDNA cloning and complete primary structure of the small, active subunit of human carboxypeptidase N (kininase 1). Europ. J. Biochem. 178: 603-607, 1989. 3. Hegele, R. A. Personal Communication. London, Ontario, Canada 2/24/2003. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CPN1 (Carboxypeptidase N Subunit 1 (CPN1))
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别名
- CPN1
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背景
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Synonyms: N-alpha-acetyltransferase 15, NatA auxiliary subunit,Gastric cancer antigen Ga19,N-terminal acetyltransferase,NMDA receptor-regulated protein 1,Protein tubedown-1,Tbdn100,NAA15,GA19, NARG1, NATH, TBDN100,
Tissue Specificity: Expressed at high levels in testis and in ocular endothelial cells. Also found in brain (corpus callosum), heart, colon, bone marrow and at lower levels in most adult tissues, including thyroid, liver, pancreas, mammary and salivary glands, lung, ovary, urogenital system and upper gastrointestinal tract. Overexpressed in gastric cancer, in papillary thyroid carcinomas and in a Burkitt lymphoma cell line (Daudi). Specifically suppressed in abnormal proliferating blood vessels in eyes of patients with proliferative diabetic retinopathy. .
Background: Carboxypeptidase N catalytic chain is an enzyme that in humans is encoded by the CPN1 gene. Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits, this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency.
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分子量
- 52 kDa
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基因ID
- 1369
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UniProt
- P15169
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途径
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process
抗原
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