BOP1 抗体 (AA 157-701)
Quick Overview for BOP1 抗体 (AA 157-701) (ABIN7600157)
抗原
See all BOP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 157-701
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原理
- Anti-BOP1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-BOP1 Antibody Picoband® (ABIN7600157). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human BOP1 recombinant protein (Position: R157-N701). Human BOP1 shares 89.9% and 89.7% amino acid (aa) sequence identity with mouse and rat BOP1, respectively.
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亚型
- IgG
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anti-Block of Proliferation 1 (BOP1) (AA 600-680) antibody
BOP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Block of Proliferation 1 (BOP1) (AA 35-84) antibodyBOP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Block of Proliferation 1 (BOP1) (N-Term) antibodyBOP1 适用: 人, 小鼠, 大鼠, 马, Pig, 犬, Bat, Drosophila melanogaster, Insect, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Block of Proliferation 1 (BOP1) (N-Term) antibodyBOP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Block of Proliferation 1 (BOP1) (N-Term) antibodyBOP1 适用: 人, 小鼠, 大鼠, 马, Pig, 犬, 兔, Saccharomyces cerevisiae, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Block of Proliferation 1 (BOP1) (N-Term) antibodyBOP1 适用: 人, 大鼠, 马, Pig, 犬, Cow, 豚鼠, 兔, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
1. Chen, B., Dragomir, M. P., Fabris, L., Bayraktar, R., Knutsen, E., Liu, X., Tang, C., Li, Y., Shimura, T., Ivkovic, T. C., Cruz de los Santos, M., Anfossi, S., and 36 others. The long noncoding RNA CCAT2 induces chromosomal instability through BOP1-AURKB signaling. Gastroenterology 159: 2146-2195, 2020. 2. Kellner, M., Rohrmoser, M., Forne, I., Voss, K., Burger, K., Muhl, B., Gruber-Eber, A., Kremmer, E., Imhof, A., Eick, D. DEAD-box helicase DDX27 regulates 3-prime end formation of ribosomal 47S RNA and stably associates with the PeBoW-complex. Exp. Cell Res. 334: 146-159, 2015. 3. Killian, A., Le Meur, N., Sesboue, R., Bourguignon, J., Bougeard, G., Gautherot, J., Bastard, C., Frebourg, T., Flaman, J.-M. Inactivation of the RRB1-pescadillo pathway involved in ribosome biogenesis induces chromosomal instability. Oncogene 23: 8597-8602, 2004. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- BOP1 (Block of Proliferation 1 (BOP1))
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别名
- BOP1
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背景
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Synonyms: BOP1, KIAA0124, Ribosome biogenesis protein BOP1, Block of proliferation 1 protein
Background: Enables RNA binding activity. Involved in regulation of cell cycle, regulation of signal transduction by p53 class mediator, and ribosomal large subunit biogenesis. Located in chromosome, nucleolus, and nucleoplasm. Part of PeBoW complex.
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分子量
- 110 kDa
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基因ID
- 23246
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UniProt
- Q14137
抗原
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