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PDPR 抗体 (AA 155-655)

PDPR 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7600150
发货至: 中国
  • 抗原 See all PDPR 抗体
    PDPR (Pyruvate Dehydrogenase Phosphatase Regulatory Subunit (PDPR))
    抗原表位
    • 8
    • 3
    • 2
    AA 155-655
    适用
    人, 小鼠, 大鼠
    宿主
    • 10
    克隆类型
    • 10
    多克隆
    标记
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDPR antibody is un-conjugated
    应用范围
    • 10
    • 8
    • 7
    • 3
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    原理
    Anti-PDPR Antibody Picoband®
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Anti-PDPR Antibody Picoband® (ABIN7600150). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human PDPR recombinant protein (Position: E155-E655). Human PDPR shares 94.4% amino acid (aa) sequence identity with mouse PDPR.
    亚型
    IgG
    Top Product
    Discover our top product PDPR Primary Antibody
  • 应用备注
    Western blot, 0.25-0.5 μg/mL, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Alazami, A. M., Patel, N., Shamseldin, H. E., Anazi, S., Al-Dosari, M. S., Alzahrani, F., Hijazi, H., Alshammari, M., Aldahmesh, M. A., Salih, M. A., Faqeih, E., Alhashem, A., and 41 others. Accelerating novel candidate gene discovery in neurogenetic disorders via whole-exome sequencing of prescreened multiplex consanguineous families. Cell Rep. 10: 148-161, 2015. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 1/17/2018. 3. Lawson, J. E., Park, S. H., Mattison, A. R., Yan, J., Reed, L. J. Cloning, expression, and properties of the regulatory subunit of bovine pyruvate dehydrogenase phosphatase. J. Biol. Chem. 272: 31625-31629, 1997.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原
    PDPR (Pyruvate Dehydrogenase Phosphatase Regulatory Subunit (PDPR))
    别名
    PDPR (PDPR 产品)
    背景

    Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

    Tissue Specificity: Expressed in all tissues.

    Background: Pyruvate dehydrogenase phosphatase regulatory subunit is a protein that in humans is encoded by the PDPR gene. Pyruvate dehydrogenase complex (PDC) catalyzes the oxidative decarboxylation of pyruvate and links glycolysis to the tricarboxylic acid cycle and fatty acid synthesis. The dephosphorylation and reactivation of PDC is catalyzed by pyruvate dehydrogenase phosphatase (PDP). The dimeric PDP has a catalytic subunit and a regulatory subunit. This gene encodes the FAD-containing regulatory subunit of PDP. The encoded protein acts to decrease the sensitivity of the PDP catalytic subunit to magnesium ions. Alternative splicing results in multiple transcript variants encoding different isoforms.

    分子量
    99 kDa
    基因ID
    55066
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