MINPP1 抗体 (AA 155-421)
Quick Overview for MINPP1 抗体 (AA 155-421) (ABIN7600148)
抗原
See all MINPP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 155-421
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原理
- Anti-MINPP1 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-MINPP1 Antibody Picoband® (ABIN7600148). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MINPP1 recombinant protein (Position: R155-H421). Human MINPP1 shares 89.5% and 89.9% amino acid (aa) sequence identity with mouse and rat MINPP1, respectively.
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
1. Appelhof, B., Wagner, M., Hoefele, J., Heinze, A., Roser, T., Koch-Hogrebe, M., Roosendaal, S. D., Dehghani, M., Mehrjardi, M. Y. V., Torti, E., Houlden, H., Maroofian, R., Rajabi, F., Sticht, H., Baas, F., Wieczorek, D., Jamra, R. A. Pontocerebellar hypoplasia due to bi-allelic variants in MINPP1. Europ. J. Hum. Genet. 29: 411-421, 2021. 2. Caffrey, J. J., Hidaka, K., Matsuda, M., Hirata, M., Shears, S. B. The human and rat forms of multiple inositol polyphosphate phosphatase: functional homology with a histidine acid phosphatase up-regulated during endochondral ossification. FEBS Lett. 442: 99-104, 1999. 3. Chi, H., Tiller, G. E., Dasouki, M. J., Romano, P. R., Wang, J., O'Keefe, R. J., Puzas, J. E., Rosier, R. N., Reynolds, P. R. Multiple inositol polyphosphate phosphatase: evolution as a distinct group within the histidine phosphatase family and chromosomal localization of the human and mouse genes to chromosomes 10q23 and 19. Genomics 56: 324-336, 1999. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MINPP1 (Multiple Inositol-Polyphosphate Phosphatase 1 (MINPP1))
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别名
- MINPP1
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背景
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Synonyms: MINPP1, MIPP, UNQ900/PRO1917, Multiple inositol polyphosphate phosphatase 1, EC 3.1.3.62, 2,3-bisphosphoglycerate 3-phosphatase, 2,3-BPG phosphatase, EC 3.1.3.80, Inositol, 1,3,4,5-tetrakisphosphate 3-phosphatase, Ins(1,3,4,5P(4 3-phosphatase
Background: his gene encodes multiple inositol polyphosphate phosphatase, an enzyme that removes 3-phosphate from inositol phosphate substrates. It is the only enzyme known to hydrolzye inositol pentakisphosphate and inositol hexakisphosphate. This enzyme also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate, an activity formerly thought to be exclusive to 2,3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Luebering shunt of the glycolytic pathway.
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分子量
- 47 kDa
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基因ID
- 9562
抗原
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