Golgin B1 (GOLGB1) (AA 153-950) 抗体
Quick Overview for Golgin B1 (GOLGB1) (AA 153-950) 抗体 (ABIN7600139)
抗原
See all Golgin B1 (GOLGB1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 153-950
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原理
- Anti-Giantin/GOLGB1 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Giantin/GOLGB1 Antibody Picoband® (ABIN7600139). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Giantin/GOLGB1 recombinant protein (Position: L153-E950).
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亚型
- IgG
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应用备注
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Western blot, 0.5-1 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 1-2 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Gross, M. B. Personal Communication. Baltimore, Md. 4/17/2014. 2. Lan, Y., Zhang, N., Liu, H., Xu, J., Jiang, R. Golgb1 regulates protein glycosylation and is crucial for mammalian palate development. Development 143: 2344-2355, 2016. 3. Linstedt, A. D., Hauri, H.-P. Giantin, a novel conserved Golgi membrane protein containing a cytoplasmic domain of at least 350 kDa. Molec. Biol. Cell 4: 679-693, 1993. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Golgin B1 (GOLGB1)
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别名
- GOLGB1
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背景
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Synonyms: Transforming growth factor beta activator LRRC32, Garpin, Glycoprotein A repetitions predominant, GARP, Leucine-rich repeat-containing protein 32, LRRC32, D11S833E
Tissue Specificity: Heart, placenta, skeletal muscle, kidney, lung and pancreas.
Background: Giantin or Golgin subfamily B member 1 is a protein that in humans is encoded by the GOLGB1 gene. GOLGB1, also known as Giantin and Macrogolgin, is a 360 to 400 kDa member of the Golgin protein family. GOLGB1 is an integral component of the Golgi membrane that associates with the cytoskeleton. It may be involved in both forming intercisternal cross-bridges that mediate stacking in Golgi complexes, and in reorganizing the complexes after they fragment during mitosis. GOLGB1 has also been identified as an autoantigen in chronic rheumatoid arthritis, and in the autoimmune disease Sjoegren syndrome. Human GOLGB1 is 3259 amino acids (aa) in length, and over aa 1596-1702, shares 92 % and 91 % sequence identity with its mouse and rat orthologs, respectively.
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分子量
- 376 kDa
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基因ID
- 2804
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UniProt
- Q14789
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途径
- SARS-CoV-2 Protein Interactome
抗原
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