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FXR2 抗体 (AA 153-651)

This anti-FXR2 antibody is a 兔 多克隆 antibody detecting FXR2 in WB, ELISA 和 FACS. Suitable for 人, 小鼠 和 猴.
产品编号 ABIN7600138
发货至: 中国

Quick Overview for FXR2 抗体 (AA 153-651) (ABIN7600138)

抗原

See all FXR2 抗体
FXR2 (Fragile X Mental Retardation, Autosomal Homolog 2 (FXR2))

适用

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人, 小鼠, 猴

宿主

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克隆类型

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多克隆

标记

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This FXR2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    AA 153-651

    原理

    Anti-FXR2 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-FXR2 Antibody Picoband® (ABIN7600138). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human FXR2 recombinant protein (Position: N153-K651).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Monkey
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Mouse
    ELISA, 0.1-0.5 μg/mL, -
    1. Bontekoe, C. J. M., McIlwain, K. L., Nieuwenhuizen, I. M., Yuva-Paylor, L. A., Nellis, A., Willemsen, R., Fang, Z., Kirkpatrick, L., Bakker, C. E., McAninch, R., Cheng, N. C., Merriweather, M., Hoogeveen, A. T., Nelson, D., Paylor, R., Oostra, B. A. Knockout mouse model for Fxr2: a model for mental retardation. Hum. Molec. Genet. 11: 487-498, 2002. 2. Darnell, J. C., Fraser, C. E., Mostovetsky, O., Darnell, R. B. Discrimination of common and unique RNA-binding activities among fragile X mental retardation protein paralogs. Hum. Molec. Genet. 18: 3164-3177, 2009. 3. Kirkpatrick, L. L., McIlwain, K. A., Nelson, D. L. Comparative genomic sequence analysis of the FXR gene family: FMR1, FXR1, and FXR2. Genomics 78: 169-177, 2001.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    FXR2 (Fragile X Mental Retardation, Autosomal Homolog 2 (FXR2))

    别名

    FXR2

    背景

    Synonyms: Sodium- and chloride-dependent GABA transporter 1,GAT-1,Solute carrier family 6 member 1,SLC6A1,GABATR, GABT1, GAT1,

    Tissue Specificity: Expressed in many tissues, highest levels in skeletal muscle.

    Background: Fragile X mental retardation syndrome-related protein 2 is a protein that in humans is encoded by the FXR2 gene. The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X cognitive disability syndrome.

    分子量

    93 kDa

    基因ID

    9513

    UniProt

    P51116
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