HNRNPL 抗体 (AA 152-569)
Quick Overview for HNRNPL 抗体 (AA 152-569) (ABIN7600130)
抗原
See all HNRNPL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 152-569
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原理
- Anti-hnRNP L/HNRNPL Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-hnRNP L/HNRNPL Antibody Picoband® (ABIN7600130). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human hnRNP L/HNRNPL recombinant protein (Position: N152-N569).
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亚型
- IgG
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anti-Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL) (AA 282-589) antibody
HNRNPL 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL) (N-Term) antibodyHNRNPL 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL) antibodyHNRNPL 适用: 人, 小鼠, 大鼠, Newt WB, ELISA, IF, IHC (p), IP, FACS, ICC, IHC (fro) 宿主: 小鼠 Monoclonal 4D11 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL) antibodyHNRNPL 适用: 人, 小鼠, 非洲爪蟾 WB, ELISA, IF, IHC (p), IP, ICC 宿主: 小鼠 Monoclonal 1G11 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL) (AA 1-558) antibodyHNRNPL 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL) (N-Term) antibodyHNRNPL 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL) (N-Term) antibodyHNRNPL 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL) (AA 89-335) antibodyHNRNPL 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL) antibodyHNRNPL 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL) (AA 249-277) antibodyHNRNPL 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20811 unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hamilton, B. J., Nichols, R. C., Tsukamoto, H., Boado, R. J., Pardridge, W. M., Rigby, W. F. C. hnRNP A2 and hnRNP L bind the 3-prime UTR of glucose transporter 1 mRNA and exist as a complex in vivo. Biochem. Biophys. Res. Commun. 261: 646-651, 1999. 2. Li, Z., Chao, T.-C., Chang, K.-Y., Lin, N., Patil, V. S., Shimizu, C., Head, S. R., Burns, J. C., Rana, T. M. The long noncoding RNA THRIL regulates TNF-alpha expression through its interaction with hnRNPL. Proc. Nat. Acad. Sci. 111: 1002-1007, 2014. 3. Pinol-Roma, S., Swanson, M. S., Gall, J. G., Dreyfuss, G. A novel heterogeneous nuclear RNP protein with a unique distribution on nascent transcripts. J. Cell Biol. 109: 2575-2587, 1989. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))
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别名
- HNRNPL
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背景
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Synonyms: Heterogeneous nuclear ribonucleoprotein L,hnRNP L,HNRNPL,HNRPL,P/OKcl.14,
Tissue Specificity: Detected in vascular smooth muscle and striated muscle. Detected in insulin-producing beta-cells in pancreas islets of Langerhans (at protein level). Widely expressed. Weakly expressed in leukocytes and fetal thymus.
Background: Heterogeneous nuclear ribonucleoprotein L is a protein that in humans is encoded by the HNRNPL gene. Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.
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分子量
- 68 kDa
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基因ID
- 3191
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UniProt
- P14866
抗原
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