PCBP1 抗体 (AA 152-268)
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北京 101111
Quick Overview for PCBP1 抗体 (AA 152-268) (ABIN7600127)
抗原
See all PCBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 152-268
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原理
- Anti-PCBP1 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PCBP1 Antibody (ABIN7600127). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PCBP1 recombinant protein (Position: P152-K268).
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亚型
- IgG
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anti-Poly(rC) Binding Protein 1 (PCBP1) (Middle Region) antibody
PCBP1 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 100-200) antibodyPCBP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 181-280) antibodyPCBP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 181-280) antibodyPCBP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 208-257) antibodyPCBP1 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) antibodyPCBP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) antibodyPCBP1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 223-234) antibodyVerified PCBP1 适用: 人, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 234-247) antibodyVerified PCBP1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 201-250) antibodyPCBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.005 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))
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别名
- PCBP1
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背景
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Synonyms: Cadherin-5, Vascular endothelial cadherin, VE-cadherin, CD144, Cdh5
Tissue Specificity: Endothelial tissues and brain.
Background: Poly (rC)-binding protein 1 is a protein that in humans is encoded by the PCBP1 gene. This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly (rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.
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分子量
- 40 kDa
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基因ID
- 5093
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UniProt
- Q15365
抗原
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