PCBP1 抗体 (AA 152-268)
Quick Overview for PCBP1 抗体 (AA 152-268) (ABIN7600127)
抗原
See all PCBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 152-268
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原理
- Anti-PCBP1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PCBP1 Antibody Picoband® (ABIN7600127). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PCBP1 recombinant protein (Position: P152-K268).
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亚型
- IgG
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anti-Poly(rC) Binding Protein 1 (PCBP1) (Middle Region) antibody
PCBP1 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 181-280) antibodyPCBP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 100-200) antibodyPCBP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 181-280) antibodyPCBP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 208-257) antibodyPCBP1 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) antibodyPCBP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 223-234) antibodyVerified PCBP1 适用: 人, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) antibodyPCBP1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 234-247) antibodyVerified PCBP1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 201-250) antibodyPCBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Chkheidze, A. N., Liebhaber, S. A. A novel set of nuclear localization signals determine distributions of the alpha-CP RNA-binding proteins. Molec. Cell. Biol. 23: 8405-8415, 2003. 2. Hahm, K., Kim, G., Turck, C. W., Smale, S. T. Isolation of a murine gene encoding a nucleic acid-binding protein with homology to hnRNP K. Nucleic Acids Res. 21: 3894 only, 1993. 3. Kosturko, L. D., Maggipinto, M. J., Korza, G., Lee, J. W., Carson, J. H., Barbarese, E. Heterogeneous nuclear ribonucleoprotein (hnRNP) E1 binds to hnRNP A2 and inhibits translation of A2 response element mRNAs. Molec. Biol. Cell 17: 3521-3533, 2006 -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.005 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))
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别名
- PCBP1
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背景
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Synonyms: Cadherin-5, Vascular endothelial cadherin, VE-cadherin, CD144, Cdh5
Tissue Specificity: Endothelial tissues and brain.
Background: Poly (rC)-binding protein 1 is a protein that in humans is encoded by the PCBP1 gene. This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly (rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.
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分子量
- 40 kDa
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基因ID
- 5093
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UniProt
- Q15365
抗原
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