ACPP 抗体 (AA 150-386)
Quick Overview for ACPP 抗体 (AA 150-386) (ABIN7600122)
抗原
See all ACPP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 150-386
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原理
- Anti-PAP/ACP3 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-PAP/ACP3 Antibody Picoband® (ABIN7600122). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PAP/ACP3 recombinant protein (Position: E150-D386).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Fong, L., Brockstedt, D., Benike, C., Breen, J. K., Strang, G., Ruegg, C. L., Engleman, E. G. Dendritic cell-based xenoantigen vaccination for prostate cancer immunotherapy. J. Immun. 167: 7150-7156, 2001. 2. Li, S. S.-L., Sharief, F. S. The prostatic acid phosphatase (ACPP) gene is localized to human chromosome 3q21-q23. Genomics 17: 765-766, 1993. 3. Munch, J., Rucker, E., Standker, L., Adermann, K., Goffinet, C., Schindler, M., Wildum, S., Chinnadurai, R., Rajan, D., Specht, A., Gimenez-Gallego, G., Sanchez, P. C., and 9 others. Semen-derived amyloid fibrils drastically enhance HIV infection. Cell 131: 1059-1071, 2007. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- ACPP (Acid Phosphatase, Prostate (ACPP))
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别名
- ACP3
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背景
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Synonyms: E3 ubiquitin-protein ligase TRIM21, 52 kDa Ro protein, 52 kDa ribonucleoprotein autoantigen Ro/SS-A, RING finger protein 81, RING-type E3 ubiquitin transferase TRIM21, Ro (SS-A), Sjoegren syndrome type A antigen, SS-A, Tripartite motif-containing protein 21, TRIM21, RNF81, RO52, SSA1
Tissue Specificity: Isoform 1 and isoform 2 are expressed in fetal and adult heart and fetal lung.
Background: Prostatic acid phosphatase (PAP), also prostatic specific acid phosphatase (PSAP), is an enzyme produced by the prostate. This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway.
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分子量
- 45-50 kDa
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基因ID
- 55
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UniProt
- P15309
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途径
- Synaptic Membrane, Ribonucleoside Biosynthetic Process
抗原
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